Results 81 to 90 of about 7,100,026 (283)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Analysis of Big Data Platform Implementation and Operation
Dianxin kexue, 2014 Big data is transiting from emerging technology to large-scale production operations. The implementation and operation of shared infrastructure platform becomes key factors for successfully deploying big data.
Yong Chen, Ang Gao
doaj
Modelling for evaluations of call center for public traffic and transport systems
Technological and Economic Development of Economy, 2011 This paper is dealing with functional organization of a call center based on human operator work. Due to significant fluctuations of user demands during the day and from day to day, the determination of required number of agents appears as actual giving ...
Slaven Tica +3 more
doaj +1 more source
Comment: The New York City Housing Part: New Remedy for an Old Dilemma [PDF]
, 1975 This Comment describes the practical operation of the Housing Part of the Civil Court of the City of New York, which began its operation October 1, 1973.
Milton, Dennis E.
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Toral rank conjecture for moment-angle complexes
, 2009 We consider an operation K \to L(K) on the set of simplicial complexes, which we call the "doubling operation". This combinatorial operation has been recently brought into toric topology by the work of Bahri, Bendersky, Cohen and Gitler on generalised ...
A. Bahri, M. Bendersky, F. R. Cohen, S. Gitler +5 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source