Results 171 to 180 of about 3,338,059 (292)

Trauma Systems in Conflict Zones: A Qualitative Study of Field Operational Requirements in Humanitarian Care. [PDF]

World J Surg
Markou-Pappas N, Ansaloni L, Ragazzoni L, Barone-Adesi F, Lamine H.   +4 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Delivering an effective violence prevention intervention at scale: testing an alternative delivery model for the Good School Toolkit in Uganda. [PDF]

BMJ Glob Health
Pearlman J, Nevatia T, Amollo M, Muluusi H, Akim A, Nakuti J, Apota JB, Odong GM, Opobo T, Opondo C, Allen E, Nakanjako PJ, Tanton C, Devries K.   +13 more
europepmc   +1 more source

Human resources development operational programme [PDF]

, 2004
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core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Integrating Space Sexology Into Long-Duration Mission Architecture: A Five-Pillar Operational Framework. [PDF]

Cureus
Minoretti P.
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Research on the drilling pipe health monitoring and intelligent life prediction management platform. [PDF]

Sci Rep
Gao X, Wu X, Li Q, Wang L, Zhu Z, Qu F.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

''Sugar for the Heart'', a bitter pill for tenecteplase: the crystallisation trap of pre-hospital fibrinolysis. [PDF]

Scand J Trauma Resusc Emerg Med
Prevautel T, Adet A, Michoud G.
europepmc   +1 more source