Results 71 to 80 of about 97,874 (341)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Derivation of a tangent function using an integrated circuit four-quadrant multiplier [PDF]
, 1973 A tangent function generator is provided which utilizes input signals proportionate to the sine and cosine of a given angle. The equipment accomplishes a trigonometric manipulation which forms an output signal substantially independent of the input ...
Bregman, B. J.
core +1 more source
Surrogate modeling of RF circuit blocks [PDF]
, 2010 Surrogate models are a cost-effective replacement for expensive computer simulations in design space exploration. Literature has already demonstrated the feasibility of accurate surrogate models for single radio frequency (RF) and microwave devices ...
Croon, Jeroen A +3 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Design of a low offset operational amplifier for current detection
Dianzi Jishu YingyongAiming at the requirement of current detection for operational amplifier performance, a new low offset operational amplifier circuit is proposed. The closed-loop current sampling circuit is composed of low-loss op-amp, PMOS tube and resistor.
Li Xin, Yu Chen, Yang Senlin
doaj +1 more source
Chaos in a Non-Autonomous Inductorless Active-RC Circuit
Active and Passive Electronic Components, 1995 Chaotic performance of a simple inductorless active-RC non-autonomous electronic circuit is reported. The circuit uses two operational amplifiers, an operational transconductance amplifier, a diode, two resistors, and one capacitor only.
Muhammad Taher Abuelma'atti +1 more
doaj +1 more source
Coulometer battery state-of-charge indicator [PDF]
, 1970 Mercury-column electrochemical coulometer is a linear ampere-hour integrating device consisting of a sealed glass tube containing two columns of mercury separated by a gap containing an electrolyte. The drive circuit uses operational amplifier techniques
Birchenough, A. G., Secunde, R.
core +1 more source
Assessment of ecosystem integrity of lowland dipterocarp forest ecosystem using remote sensing [PDF]
, 2021 Ecosystem Integrity Index (EII) is a concept to determine the quality or the health of an ecosystem. The EII development can assist forest managers and decision makers in the conservation effort and forest management in Malaysia through the development ...
Abdul Razak, Muhammad Azmil
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source