Results 91 to 100 of about 76,908 (313)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Methodology of fault diagnosis for grid-connected photovoltaic systems of network connection
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2020 The aim of the present research work is the design of a methodology of fault diagnosis as a contribution to the improvement of indicators about efficiency, maintenance and availability of Photovoltaic Systems of Network Connection (PVSNC).
J. R. Núñez A. +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Strategies to Increase Early Discharges to Reduce Avoidable Patient Days and Improve Patient Flow [PDF]
, 2018 CREATING ALGORITHMS TO INCREASE THE NUMBERS OF HOSPITAL MORNING DISCHARGES RESULTING IN IMPROVED PATIENT FLOW Discharging a percentage of patients early in the day helps to improve patient flow.
Nayak, Suneela +9 more
core +1 more source
On a Biparametric Appell Extension: Analytical Properties and Structural Analysis
AxiomsThis paper introduces and investigates a novel two-parameter sequence, termed the biparametric Appell extension (B-App-Ex) and denoted by Bn(x;λ,α). Standard classical Appell sequences often lack sufficient structural parameters, which can limit their ...
Hany Mostafa Ahmed
doaj +1 more source
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
REDUCTION FOR NATURAL OPERATORS ON PROJECTABLE CONNECTIONS
Demonstratio Mathematica, 2009 AbstractWe present a very simple proof of a general reduction for natural operators on torsion free projectable classical linear connections.
Mikulski, Włodzimierz, Tomáš, J.
openaire +2 more sources