Results 111 to 120 of about 76,908 (313)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The natural operators of general affine connections into general affine connections
Annales Universitatis Mariae Curie-Sklodowska, sectio A – Mathematica, 2017 We reduce the problem of describing all \(\mathcal{M} f_m\)-natural operators transforming general affine connections on \(m\)-manifolds into general affine ones to the known description of all \(GL(\mathbf{R}^m)\)-invariant maps \(\mathbf{R}^{m*}\otimes \mathbf{R}^m\to \otimes^k\mathbf{R}^{m*}\otimes\otimes ^k\mathbf{R}^m\) for \(k=1,3\).
Kurek, Jan, Mikulski, Włodzimierz M.
openaire +3 more sources
A heuristic and an exact method for the gate matrix connection cost minimization problem [PDF]
, 2013 In many applications, a sequencing of patterns (electronic circuit nodes, cutting patterns, product orders, etc.) has to be found in order to optimize some given objective function, giving rise to the so-called open stack problems.
DE GIOVANNI, LUIGI +17 more
core +1 more source
European Spatial Research and PolicyThis article focuses on a very narrowly specific segment of this issue, considering the impacts of HSR in the long term, not as transport arteries connecting the most important metropolitan areas but, on the contrary, as an internal factor of development
Martin Vrána +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Frontiers of Architectural Research, 2016 This study examines the interrelatedness between the hierarchical structure of China׳s urban system and high-speed railway (HSR) network planning at the national level. As a multi-layered system, the Chinese HSR can be categorized into three sub-networks,
Hong Sun
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Strategies to Improve Post-procedural Safe Patient Handoffs [PDF]
, 2018 STRATEGIES TO IMPROVE SAFE PATIENT HANDOFFS AND POST PROCEDURAL FLOW During patient transfers from one care unit to another, it is imperative for patient safety and satisfaction that timely and complete communication between staff occurs.
Herman, Tara +6 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Egnatia Highway and Pan-European Corridor 8: Complementarity Or Competition? [PDF]
The modern economical status and needs of regional development in Greece and the broader geographical area demand a high capacity highway, capable of fulfilling high speed requirements.
Michalis Karakotsoglou +2 more
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