Results 101 to 110 of about 2,297,961 (309)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Reflections on operational research
, 1980 This chapter looks at operational ...
Dando, Malcolm, Eden, Colin
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
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The natural operators of general affine connections into general affine connections
Annales Universitatis Mariae Curie-Sklodowska, sectio A – Mathematica, 2017 We reduce the problem of describing all \(\mathcal{M} f_m\)-natural operators transforming general affine connections on \(m\)-manifolds into general affine ones to the known description of all \(GL(\mathbf{R}^m)\)-invariant maps \(\mathbf{R}^{m*}\otimes \mathbf{R}^m\to \otimes^k\mathbf{R}^{m*}\otimes\otimes ^k\mathbf{R}^m\) for \(k=1,3\).
Kurek, Jan, Mikulski, Włodzimierz M.
openaire +3 more sources
Battle flags hanging in Ohio History Center plaza
, 1970 Photograph of Ohio's Battle Flag collection hanging in the plaza of the Ohio History Center in Columbus, Ohio, ca. 1970. The flags were displayed on the Center’s plaza level from the time the building opened in 1970 through the late 1980s, when they were
Ohio History Connection
core
European Spatial Research and PolicyThis article focuses on a very narrowly specific segment of this issue, considering the impacts of HSR in the long term, not as transport arteries connecting the most important metropolitan areas but, on the contrary, as an internal factor of development
Martin Vrána +4 more
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Research of the Power Plant Operational Modes
MATEC Web of Conferences, 2017 In this article the algorithm of the power plant operational modes research is offered. According to this algorithm the program for the modes analysis and connection power transformers choice is developed. The program can be used as educational means for
Koismynina Nina M., Valiev Timur T.
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Frontiers of Architectural Research, 2016 This study examines the interrelatedness between the hierarchical structure of China׳s urban system and high-speed railway (HSR) network planning at the national level. As a multi-layered system, the Chinese HSR can be categorized into three sub-networks,
Hong Sun
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