Results 121 to 130 of about 3,661,265 (345)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
FMEA of gasketed and non-gasketed bolted flanged pipe joints [PDF]
, 2005 Limited work is available in the literature on the Failure Mode and Effects Analysis of bolted flanged pipe joints. From previous comparative reliability studies of both gasketed and non-gasketed bolted flanged pipe joints, generally it is found that ...
Abid, Muhammad, Nash, David
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Research of the Power Plant Operational Modes
MATEC Web of Conferences, 2017 In this article the algorithm of the power plant operational modes research is offered. According to this algorithm the program for the modes analysis and connection power transformers choice is developed. The program can be used as educational means for
Koismynina Nina M., Valiev Timur T.
doaj +1 more source
Inequalities connected with averaging operators. Part II
Indagationes Mathematicae, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Unbounded products of operators and connections to Dirac-type operators
Bulletin des Sciences Mathématiques, 2014 Let $A$ and $B$ be two densely defined unbounded closeable operators in a Hilbert space such that their unbounded operator products $AB$ and $BA$ are also densely defined. Then all four operators possess adjoints and we obtain new inclusion bounds for the operator product closures $\bar{A} \bar{B}$ and $\bar{AB}$ in terms of new relations among the ...
Gustafson, Karl, Mortad, Mohammed Hichem
openaire +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2013 The paper considers problems pertaining to modeling and simulation of operational hybrid system modes of the distributed generation comprising conventional sources – modular diesel generators, gas-turbine power units; and renewable sources – wind and ...
A. M. Gashimov +2 more
doaj
European Spatial Research and PolicyThis article focuses on a very narrowly specific segment of this issue, considering the impacts of HSR in the long term, not as transport arteries connecting the most important metropolitan areas but, on the contrary, as an internal factor of development
Martin Vrána +4 more
doaj +1 more source