Results 141 to 150 of about 76,908 (313)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Generalized connected operators
, 1996 This paper deals with the notion of connected operators These operators are becoming popular in image processing because they have the fundamental property of simplifying the signal while preserving the contour information In a rst step we recall the basic notions involved in binary and gray level connected operators.
Oliveras Vergés, Albert +1 more
openaire +1 more source
Operational risk and e-banking [PDF]
, 2010 Banking involves a variety of risks. Under Basel II, the main risks are the monitored credit risk, market risk and operational risk. Frequently, operational risks are underestimated, considering that they would not affect the optimal activity of a bank ...
Şerbu, R., Tănase, R. D.
core
Journal of Patient ExperiencePatient complaints are valuable sources of information for quality improvement and provide an avenue for patient self-advocacy. This paper outlines the development and implementation of a novel training program, termed CODE (Compassion, Operational ...
Richard M. Elias MBBS, MPH +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Satellite system performance assessment for in-flight entertainment and air traffic control [PDF]
, 2007 Concurrent satellite systems have been proposed for IFE (In-Flight Entertainment) communications, thus demonstrating the capability of satellites to provide multimedia access to users in aircraft cabin. At the same time, an increasing interest in the use
Pirovano, Alain +3 more
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Iranian Journal of Electrical and Electronic Engineering, 2006 This paper presents the effects of instrument transformers connection points on the measured impedance by distance relays in the presence of Flexible Alternating Current Transmission System (FACTS) devices with series connected branch.
H. Shateri, S. Jamali
doaj