Results 131 to 140 of about 1,864,391 (308)

Advanced Concepts for Ultra-Wide-Swath SAR Imaging [PDF]

open access: yes, 2008
This paper reviews advanced multi-channel SAR system concepts for the imaging of ultra-wide swaths with high azimuth resolution. Novel system architectures and operational modes are introduced and compared to each other with regard to their ...
Bordoni, Federica   +5 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Paving the way to better understand the effects of prolonged spaceflight on operational performance and its neural bases. [PDF]

open access: yesNPJ Microgravity, 2023
Stahn AC   +6 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Assessing the Impact of Nigerian Seaports’ Operational Performance on the Construction Sector’s Contribution to GDP

open access: yesCSID Journal of Infrastructure Development
The construction sector in Nigeria relies heavily on imported materials; however, inefficiencies and frequent delays at the seaports have led to increased costs, significantly affecting the sector’s contribution to the nation’s Gross Domestic Product ...
Ismail Gbolahan Dere   +1 more
doaj   +1 more source

How Effective are Toll Roads in Improving Operational Performance? [PDF]

open access: yes, 2019
The main focus of this research is to develop a systematic analytical framework and evaluate the effect of a toll road on region’s traffic using travel time and travel time reliability measures. The travel time data for the Triangle Expressway in Raleigh,
Mathew, Sonu, Pulugurtha, Srinivas S.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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