Results 141 to 150 of about 10,006,314 (254)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Operational Performance of a Compact Proton Therapy System: A 5-Year Experience. [PDF]

Int J Part Ther, 2022
Zeidan OA, Pepmiller E, Willoughby T, Li Z, Burkavage J, Harper B, Fraser M, Moffatt K, Meeks SL, Ramakrishna N.   +9 more
europepmc   +1 more source

When Diagnosis Meets Reality: Operational Performance of Routine Malaria Diagnostics Against Molecular Evidence in Southwestern Saudi Arabia. [PDF]

J Trop Med
Ayashi MA, Muyidi AA, Wakid MH, Baakdah FM, Alghanmi MS, Gattan HS, Zalah AA, Wasili EEA, Bajawi AY, Brek TM.   +9 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Analytical and numerical approach to corporate operational risk modelling [PDF]

Although The New Basel Accord gives the methodology for managing operational risk in financial institutions, corporate risk seems not to be recognized enough. In this Ph.D.
Pawel Mista
core  

Changes in the Composition of the WIG20 and mWIG40 Indices and the Operational Performance of Newly Added Companies

Nauki o Finansach
Aim: This article investigates whether the transition of companies from the mWIG40 index to the more prestigious WIG20 index affects their operational efficiency.
Ewa Blaszke
doaj  

Supply chain integration practices and its impact on financial and operational performance of the Tunisian industrial sector

Accounting
Supply chain integration is a key factor in improving business performance. Despite this growing interest, little research has highlighted this issue that will determine the survival of many companies.
Rim Ghariani, Younes Boujelbene
doaj   +1 more source

Utilization and Operational Performance of the 988 Suicide & Crisis Lifeline in Nevada: A Retrospective Descriptive Analysis. [PDF]

Cureus
Toro Ruilowa OA, Chea D, Atkins JB, Durette L.   +3 more
europepmc   +1 more source

The system-wide effects of dispatch, response and operational performance on emergency medical services during Covid-19. [PDF]

Humanit Soc Sci Commun, 2022
Pitt IL.
europepmc   +1 more source