Results 151 to 160 of about 10,006,314 (254)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Operational performance of GeneXpert for tuberculosis diagnosis in West Java province, Indonesia: a public health evaluation. [PDF]

BMC Health Serv Res
Nijman G, Alifia A, Annisa SN, Shurianto L, de Boer IE, Puspitasari I, Indriani S, Alisjahbana B, van Crevel R, Hill PC, Lestari BW.   +10 more
europepmc   +1 more source

Evaluating the long-term operational performance of a large-scale inland terminal: A discrete event simulation-based modeling approach. [PDF]

PLoS One, 2022
Srisurin P, Pimpanit P, Jarumaneeroj P.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Lipase Stability in Structured Lipid Synthesis: The Interplay of Substrate Characteristics and Strategies to Improve Its Operational Performance-A Critical Review. [PDF]

J Food Sci
Lee EL, Chan ES, Siow LF, Song CP, Lee YY.   +4 more
europepmc   +1 more source

The influencing mechanism of big data analytics technology capability on enterprise's operational performance: The mediating role of data-tool fit. [PDF]

Front Psychol, 2022
Huang X, Yang S, Wang J, Lin F, Jiang Y.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis. [PDF]

Front Nutr
Wang R, Wang W, Meng L, Hao G, Gu G.
europepmc   +1 more source

Operational Performance and Load Flexibility Analysis of Japanese Zero Energy House. [PDF]

Int J Environ Res Public Health, 2021
Zhang X, Gao W, Li Y, Wang Z, Ushifusa Y, Ruan Y.   +5 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source