Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Assessment and benchmarking of freight transport operations: The case of Pan-European Corridors IV, V and VII [PDF]
, 2013 Sustainable freight transport via co-modality is gaining more importance in the South East Europe (SEE) region. However, there are not adequate studies that analyze the status of the SEE transport corridors as well as assess and benchmark their ...
Minis, I. +5 more
core
Influence of Employees' Intention to Adopt AI Applications and Big Data Analytical Capability on Operational Performance in the High-Tech Firms. [PDF]
J Knowl Econ, 2023 Chen CH.
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Impacts of COVID-19 on the Operational Performance of Express Lanes and General-Purpose Lanes. [PDF]
Transp Res Rec, 2023 Kodi JH, Kitali AE, Kidando E, Alluri P.
europepmc +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Performance measurement and improvement in the management of bank networks using data envelope analysis [PDF]
This aim of this thesis is to develop a comprehensive methodology for assessing performance and setting targets in multi-unit organisations in the financial sector.
Camanho, Ana Maria Cunha Ribeiro dos Santos Ponces
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An investigation of the integration of business intelligence tools with the roles of performance management of wholesale SMEs in the UK: to enhance decision making that maintains/improves operational performance [PDF]
This thesis investigates the role of business intelligence tools (BI) in performance management activities within small to medium enterprises(SME). The purpose of this investigation is to align the features of BI tools with the performance management ...
AL-Majali, Faris
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source