The system-wide effects of dispatch, response and operational performance on emergency medical services during Covid-19. [PDF]
Humanit Soc Sci Commun, 2022 Pitt IL.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Enhancing the Company's Financial Performance of Supply Chain Operations: A Case Study of an Egyptian Manufacturing Company [PDF]
A limited number of studies have been conducted to demonstrate the potential impact of managing supply chain (SC) day-to-day practices on improving a company's financial performance.
Elgazzar, Sara H.
core
Evaluating the long-term operational performance of a large-scale inland terminal: A discrete event simulation-based modeling approach. [PDF]
PLoS One, 2022 Srisurin P, Pimpanit P, Jarumaneeroj P.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The influencing mechanism of big data analytics technology capability on enterprise's operational performance: The mediating role of data-tool fit. [PDF]
Front Psychol, 2022 Huang X, Yang S, Wang J, Lin F, Jiang Y.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Nauki o FinansachAim: This article investigates whether the transition of companies from the mWIG40 index to the more prestigious WIG20 index affects their operational efficiency.
Ewa Blaszke
doaj
AccountingSupply chain integration is a key factor in improving business performance. Despite this growing interest, little research has highlighted this issue that will determine the survival of many companies.
Rim Ghariani, Younes Boujelbene
doaj +1 more source