Results 41 to 50 of about 115,127 (263)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Weather as a factor in the history of warfare [PDF]
Војно дело, 2016 Outcomes of military operations throughout the history, both on land and at sea, have depended to a large extent on weather conditions. Weather, as a meteorological factor, has always been important for the use of military units, and the achievement of ...
Komljenović Slaven, Ćurčić Jovica
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Energies, 2017 The concept of virtual power plant (VPP) has been proposed to facilitate the integration of distributed renewable energy. VPP behaves similar to a single entity that aggregates a collection of distributed energy resources (DERs) such as distributed ...
Jing Qiu +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Energies, 2019 Flexible distributed energy resources, such as energy storage systems (ESSs), are increasingly considered as means for mitigating challenges introduced by the integration of stochastic, variable distributed generation (DG).
Iver Bakken Sperstad, Magnus Korpås
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Energies, 2020 This paper proposes a mathematical model in order to simulate Day-ahead markets of large-scale multi-energy systems with a high share of renewable energy. Furthermore, it analyses the importance of including unit commitment when performing such analysis.
Juan Gea-Bermúdez +3 more
doaj +1 more source