Results 61 to 70 of about 115,127 (263)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

PLANNING SYSTEM DEVELOPMENT UNDER THE CONDITIONS OF INSTABILITY

Russian Journal of Economics and Law, 2010
The article presents a complex approach to the formation of in-company planning system under modern conditions. The problem aspects of long-term and short-term goals coordination are defined, the ways of solving contradictions are grounded.
M. F. Salakhieva
doaj  

Operational Planning and Bidding for District Heating Systems with Uncertain Renewable Energy Production

Energies, 2018
In countries with an extended use of district heating (DH), the integrated operation of DH and power systems can increase the flexibility of the power system, achieving a higher integration of renewable energy sources (RES).
Ignacio Blanco, Daniela Guericke, Anders N. Andersen, Henrik Madsen   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cooperative Operational Planning of Interruptible Load Contracts for Enhancing Performance Reliability of Multi-Microgrid Power Distribution Systems

IEEE Access
This paper evaluates the benefits of cooperative utilization of available flexibility for enhancing the performance reliability of Multi-Microgrid (MMG) distribution systems in emergency situations. Interruptible Load Contracts (ILCs) with voluntary load
Mahdi Farrokhi, Mahmoud Fotuhi-Firuzabad, Amir Safdarian, Payman Dehghanian   +3 more
doaj   +1 more source

Green, Yellow, and Woody Biomass Supply-Chain Management: A Review

Energies, 2019
Various sources of biomass contribute significantly in energy production globally given a series of constraints in its primary production. Green biomass sources (such as perennial grasses), yellow biomass sources (such as crop residues), and woody ...
Efthymios Rodias, Remigio Berruto, Dionysis Bochtis, Alessandro Sopegno, Patrizia Busato   +4 more
doaj   +1 more source

A hierarchical model for strategic and operational planning in blood transportation with drones. [PDF]

PLoS One, 2023
Amirsahami A, Barzinpour F, Pishvaee MS.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source