Results 91 to 100 of about 602,372 (317)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Abordări privind absorbția fondurilor structurale în România în perioada 2007-2013

open access: yesRevista Transilvană de Ştiinţe Administrative, 2013
This article is trying to generally approach the structural funds in Romania between 2007 and 2013. The structural funds’ allocation in 2014 will be almost 988 euros per capita, 114.4 euros less than the current programming period has anticipated.
Bianca GELĂMANCĂ, Paul ZAI
doaj  

Resource management in software-programmable router operating systems

open access: yesIEEE Journal on Selected Areas in Communications, 2001
Future routers will not only forward data packets but also provide value-added services, such as security, accounting, caching, and resource management. These services ran be implemented as general programs, to be invoked by traversing packets embedding router program calls.
Yau, David K.Y., Chen, Xiangjing
openaire   +3 more sources

UK Large-scale Wind Power Programme from 1970 to 1990: the Carmarthen Bay experiments and the Musgrove Vertical-Axis Turbines [PDF]

open access: yes, 2006
This article describes the development of the Musgrove Vertical Axis Wind Turbine (VAWT) concept, the UK ‘Carmarthen Bay’ wind turbine test programme, and UK government’s wind power programme to 1990. One of the most significant developments in the story
Anderson M. B.   +29 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Learning Lessons from The Bangalore Urban Poverty Alleviation Programme: Participatory Approaches to Urban Development [PDF]

open access: yes, 2000
The present report contains the findings of a review study of the BUPP programme in the context of the SINPA programme. This study aims to be relevant in a practical, operational sense, first for the Bangladesh city of Tangail, then for other cities ...
Krishnamurthy, A.N., Wit, J.W. (Joop) de
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Research that influences policy and practice – characteristics of operational research to improve malaria control in Mpumalanga Province, South Africa

open access: yesMalaria Journal, 2002
Background Much communicable disease control research has had little impact on local control programme policy and practice for want of an operational component.
Speare Richard   +2 more
doaj   +1 more source

Developing the Heritage Destination: An investigation of the implementation of strategic plans [PDF]

open access: yes, 2013
This paper attempts to investigate the factors which are influential in the effective implementation of strategic planning in a heritage tourism setting. In particular, the paper looks at the respective roles of the public and private sectors in relation
Gilmore, Audrey   +2 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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