Results 141 to 150 of about 2,531,355 (284)

Operational research to strengthen evidence-based interventions to tackle antimicrobial resistance in the Region of the Americas. [PDF]

Rev Panam Salud Publica, 2023
Celis Y, Esparza G, Zachariah R, Pérez F.   +3 more
europepmc   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Quality of Reporting of Adverse Drug Reactions to Antimicrobials Improved Following Operational Research: A before-and-after Study in Sierra Leone (2017-2023). [PDF]

Trop Med Infect Dis, 2023
Conteh TA, Thomas F, Abiri OT, Komeh JP, Kanu A, Kanu JS, Fofanah BD, Thekkur P, Zachariah R.   +8 more
europepmc   +1 more source

Environmental health discipline science plan [PDF]

The purpose of this plan is to provide a conceptual strategy for NASA's Life Sciences Division research and development activities in environmental health.

core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Improvement in the Surveillance System for Livestock Diseases and Antimicrobial Use Following Operational Research Studies in Sierra Leone January-March 2023. [PDF]

Trop Med Infect Dis, 2023
Konteh SA, Bangura Turay FI, Leno A, Satyanarayana S, Nair D, Bah MA, Saidu S, Sellu-Sallu D, Gborie SR, Kamara SM, Jalloh AT, Kanu JS, Kamara KN, Moiwo MM, Dsani E, Nantima N.   +15 more
europepmc   +1 more source

Ethics outside, within or beyond OR models [PDF]

Since ethical concerns are calling for more attention within Operational Research, we present three approaches to combine Operational Research models with ethics.
Luk N. Van Wassenhove, Marc Le Menestrel
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Improvement in Infection Prevention and Control Compliance at the Three Tertiary Hospitals of Sierra Leone following an Operational Research Study. [PDF]

Trop Med Infect Dis, 2023
Kamara RZ, Kamara IF, Moses F, Kanu JS, Kallon C, Kabba M, Moffett DB, Fofanah BD, Margao S, Kamara MN, Moiwo MM, Kpagoi SSTK, Tweya HM, Kumar AMV, Terry RF.   +14 more
europepmc   +1 more source

A nonlinear trajectory command generator for a digital flight-control system [PDF]

Operational application of the command generator (CG) was examined in detail in a simulation of a flight control system with the augmentor wing jet STOL research aircraft.
Cicolani, L. S., Weissenberger, S.
core   +1 more source