Results 41 to 50 of about 494,728 (259)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Provision of emergency obstetric care at secondary level in a conflict setting in a rural area of Afghanistan – is the hospital fulfilling its role?

Conflict and Health, 2018
Background Provision of Emergency Obstetric and Neonatal Care (EmONC) reduces maternal mortality and should include three components: Basic Emergency Obstetric and Neonatal Care (BEmONC) offered at primary care level, Comprehensive EmONC (CEmONC) at ...
Daphne Lagrou, Rony Zachariah, Karen Bissell, Catherine Van Overloop, Masood Nasim, Hamsaya Nikyar Wagma, Shafiqa Kakar, Séverine Caluwaerts, Eva De Plecker, Renzo Fricke, Rafael Van den Bergh   +10 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Exposure to moral stressors and associated outcomes in healthcare workers: prevalence, correlates, and impact on job attrition

European Journal of Psychotraumatology
Introduction: Healthcare workers (HCWs) often experience morally challenging situations in their workplaces that may contribute to job turnover and compromised well-being.
Anthony Nazarov, Callista A. Forchuk, Stephanie A. Houle, Kevin T. Hansen, Rachel A. Plouffe, Jenny J. W. Liu, Kylie S. Dempster, Tri Le, Ilyana Kocha, Fardous Hosseiny, Ann Heesters, J. Don Richardson   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Sociodemographic and obstetric determinants of HIV infection among pregnant women in Cameroon: a contribution toward the elimination of vertical transmission in low- and middle-income countries

BMC Infectious Diseases
Background The risk of HIV transmission during pregnancy remains a concern in Cameroon. Recent estimates suggest a national HIV prevalence of approximately 4.5%, increasing the likelihood of vertical transmission. Objective To estimate HIV seroprevalence
Justin Ndié, Jean Pierre Yves Awono Noah, Francis Ateba Ndongo, Joseph Fokam, Alice Ketchaji, Rogacien Kana Dongmo, Jean De Dieu Anoubissi, Christian Noël Bayiha, Richard Tchapda, Tatiana Avang Nkoa Palisson, Martial Gaël Bonyohe, Caroline Teh Monteh, Njamnshi Yembe Wepnyu, Félicité Naah Tabala, Gildas Nguemkam, Hernandez Lélé Siaka, Carelle Djofang Yepndo, Audrey Raïssa Djomo Nzaddi, Daniel Offrande Mabongo, Maurice Rocher Mbella, Marie Micheline Dongmo, Ngo Issouck, Nelly Monkam, Leopoldine Madjo Oumbe, Clifford Moluh, Paul Tjek, Vittorio Colizzi, Carlo-Federico Perno, Giulia Cappelli, Nicaise Ndembi, David Kob, Gregory-Edie Halle Ekane, Basile Keugoung, Alexis Ndjolo, Serge Clotaire Billong, Céline Nkenfou, Jérôme Ateudjieu, Anne Cécile Zoung-Kanyi Bissek   +37 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source