Results 51 to 60 of about 2,142,897 (254)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Exposure to moral stressors and associated outcomes in healthcare workers: prevalence, correlates, and impact on job attrition

European Journal of Psychotraumatology
Introduction: Healthcare workers (HCWs) often experience morally challenging situations in their workplaces that may contribute to job turnover and compromised well-being.
Anthony Nazarov, Callista A. Forchuk, Stephanie A. Houle, Kevin T. Hansen, Rachel A. Plouffe, Jenny J. W. Liu, Kylie S. Dempster, Tri Le, Ilyana Kocha, Fardous Hosseiny, Ann Heesters, J. Don Richardson   +11 more
doaj   +1 more source

A Longitudinal Study of the Bladder Cancer Applying a State-Space Model with Non-Exponential Staying Time in States

Mathematics, 2021
A longitudinal study for 847 bladder cancer patients for a period of fifteen years is presented. After the first surgery, the patients undergo successive ones (recurrences).
Delia Montoro-Cazorla, Rafael Pérez-Ocón, Alicia Pereira das Neves-Yedig   +2 more
doaj   +1 more source

Provision of emergency obstetric care at secondary level in a conflict setting in a rural area of Afghanistan – is the hospital fulfilling its role?

Conflict and Health, 2018
Background Provision of Emergency Obstetric and Neonatal Care (EmONC) reduces maternal mortality and should include three components: Basic Emergency Obstetric and Neonatal Care (BEmONC) offered at primary care level, Comprehensive EmONC (CEmONC) at ...
Daphne Lagrou, Rony Zachariah, Karen Bissell, Catherine Van Overloop, Masood Nasim, Hamsaya Nikyar Wagma, Shafiqa Kakar, Séverine Caluwaerts, Eva De Plecker, Renzo Fricke, Rafael Van den Bergh   +10 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sociodemographic and obstetric determinants of HIV infection among pregnant women in Cameroon: a contribution toward the elimination of vertical transmission in low- and middle-income countries

BMC Infectious Diseases
Background The risk of HIV transmission during pregnancy remains a concern in Cameroon. Recent estimates suggest a national HIV prevalence of approximately 4.5%, increasing the likelihood of vertical transmission. Objective To estimate HIV seroprevalence
Justin Ndié, Jean Pierre Yves Awono Noah, Francis Ateba Ndongo, Joseph Fokam, Alice Ketchaji, Rogacien Kana Dongmo, Jean De Dieu Anoubissi, Christian Noël Bayiha, Richard Tchapda, Tatiana Avang Nkoa Palisson, Martial Gaël Bonyohe, Caroline Teh Monteh, Njamnshi Yembe Wepnyu, Félicité Naah Tabala, Gildas Nguemkam, Hernandez Lélé Siaka, Carelle Djofang Yepndo, Audrey Raïssa Djomo Nzaddi, Daniel Offrande Mabongo, Maurice Rocher Mbella, Marie Micheline Dongmo, Ngo Issouck, Nelly Monkam, Leopoldine Madjo Oumbe, Clifford Moluh, Paul Tjek, Vittorio Colizzi, Carlo-Federico Perno, Giulia Cappelli, Nicaise Ndembi, David Kob, Gregory-Edie Halle Ekane, Basile Keugoung, Alexis Ndjolo, Serge Clotaire Billong, Céline Nkenfou, Jérôme Ateudjieu, Anne Cécile Zoung-Kanyi Bissek   +37 more
doaj   +1 more source

ANALYZING OPERATIONAL AND FINANCIAL PERFORMANCE ON THE FINANCIAL TECHNOLOGY (FINTECH) FIRM (Case Study on Samsung Pay) [PDF]

, 2017
This study aims to analyze the operational and financial performance of Samsung Pay at United States in the year of 2015. Operational performances consist of availability, security, and effectiveness and usability of Samsung Pay.
ALIMIRRUCHI, Wahyu, KISWARA, Endang
core  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Beyond the pill: contextual effects of community-based PrEP delivery on pregnancy risk among FSWs in Cameroon – a propensity score-matched analysis

BMC Public Health
Background Female sex workers (FSWs) face elevated risks of both HIV acquisition and unintended pregnancies. While oral pre-exposure prophylaxis (PrEP) is an established HIV prevention tool, its broader impact on sexual and reproductive health (SRH ...
Jean-Pierre Yves Awono Noah, Francis Ateba Ndongo, Justin Ndié, Martial Gaël Bonyohe, Rogacien Kana Dongmo, Rodrigue Bile Komokcheua, Félicité Naah Tabala, Jérôme Ateudjieu, Anne Cécile Zoung-Kanyi Bissek   +8 more
doaj   +1 more source

Дослідження системи операційного менеджменту організації, на прикладі Apple Computer, Inc [PDF]

, 2020
The object of investigation is the process of managing of operating activities of Apple, Inc. The aim of the work is to formulate theoretical approaches and to develop practical recommendations on directions of improvement of operating management at the
Magwizi, Christina Nyaradzai, Магвізі, Крістіна Ньярадзаі   +1 more
core