Results 121 to 130 of about 1,936,418 (346)
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Effect of Pulp Protection Technique on the Clinical Performance of Amalgam Restorations: Three-Year Results [PDF]
, 2002 This study evaluated the influence of the pulp protection technique on clinical performance of amalgam restorations after three years, with particular reference to post-operative sensitivity and secondary caries.
Baratieri, L.N. +4 more
core
Operator Symbols and Operator Indices [PDF]
Symmetry, 2019 We suggest a certain variant of symbolic calculus for special classes of linear bounded operators acting in Banach spaces. According to the calculus we formulate an index theorem and give applications to elliptic pseudo-differential operators on smooth manifolds with non-smooth boundaries.
openaire +2 more sources
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
The pros and cons of suturing the ventral hernia defect using the intraperitoneal onlay mesh technique [PDF]
Vojnosanitetski PregledBackground/Aim. Laparoscopic ventral hernia surgery, including intraperitoneal onlay mesh (IPOM), is as effective and safe as open surgery, with a lower recurrence rate.
Jovanović Bojan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Frontiers in Neuroscience, 2019 Obsessive compulsive disorder (OCD) is a common, disabling psychiatric disease characterized by persistent, intrusive thoughts and ritualistic, repetitive behaviors.
Patrick J. Karas +5 more
doaj +1 more source
Adrenal Cysts: To Operate or Not to Operate?
Journal of Clinical MedicineAdrenal cysts are uncommon and usually asymptomatic, and therefore are usually incidentally discovered adrenal lesions. They have a broad pathohistological spectrum that includes pseudocysts and endothelial (vascular), parasitic, and epithelial (mesothelial) cysts.
Ivana Bozic Antic +2 more
openaire +3 more sources