Results 71 to 80 of about 733,074 (265)

Metastatic melanoma of the skin: Surgical treatment [PDF]

open access: yesVojnosanitetski Pregled, 2003
Panajotović Ljubomir
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estudo comparativo de retalhos tubulares de pele de ratos com dois tipos de cateter como molde

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVO: A tubulização de retalhos de pele é um artifício técnico muito empregado na correção de hipospádias. Existem controvérsias quanto aos riscos e benefícios do uso de sondas para moldar a neo-uretra e promover a derivação urinária.
Antonio Henrique Rodrigues dos Passos   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Replace Operator [PDF]

open access: yesProceedings of the 33rd annual meeting on Association for Computational Linguistics -, 1995
This paper introduces to the calculus of regular expressions a replace operator and defines a set of replacement expressions that concisely encode alternate variations of the operation. Replace expressions denote regular relations, defined in terms of other regular expression operators. The basic case is unconditional obligatory replacement. We develop
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Surgical Fear, Anxiety, and Satisfaction with Nursing Care: A Cross-Sectional Study of Hospitalized Surgical Patients

open access: yesNursing Reports
Background: Surgery is often accompanied by fear and anxiety, which can adversely affect recovery and patient’s well-being. Understanding the relationship between surgical fear and anxiety and satisfaction with nursing care can help nurses target ...
Ioanna Dimitriadou   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The intraoperative surgical context. Appreciations from a group of patients and from the nursing team El contexto quirúrgico transoperatorio. Apreciaciones de un grupo de pacientes y del equipo de enfermería O contexto cirúrgico intra-operatório. Apreciações de um grupo de pacientes e da equipe de enfermagem

open access: yesInvestigación y Educación en Enfermería, 2012
Objective. To interpret the experience of being unconscious or alert from a group of patients during the surgical act and appreciations from the members of the nursing team on the same context. Methodology.
Ángela María Salazar Maya
doaj  

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