Results 81 to 90 of about 1,157,536 (288)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
On Integral Operators with Operator-Valued Kernels [PDF]
Journal of Inequalities and Applications, 2010 Here Lq-Lp boundedness of integral operator with operator-valued kernels is studied and the main result is applied to convolution operators. Using these results Besov space regularity for Fourier multiplier operator is established.
openaire +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Nursing ReportsBackground: Surgery is often accompanied by fear and anxiety, which can adversely affect recovery and patient’s well-being. Understanding the relationship between surgical fear and anxiety and satisfaction with nursing care can help nurses target ...
Ioanna Dimitriadou +7 more
doaj +1 more source
To operate or not to operate, that is the question
Bone & Joint Research, 2016 To operate or not to operate, that is the question. In the case of a displaced diaphyseal fracture of the femur, this question is not a challenge. We do not need a randomised controlled trial to determine if intramedullary nailing of a fracture of the femur is more effective, for any outcome ...
Ghert, M., McKee, M.
openaire +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 1919 Physical condition: GoodIn this report, an operative working in the Mill reports on the activities of mill ...
Operative #556
core +1 more source
Surgical treatment and outcome of spinal arteriovenous malformations
Medicinski GlasnikAim A rare and diverse set of abnormalities formed by spinal blood arteries known as spinal arteriovenous malformations (AVMs) has a higher risk of haemorrhage and morbidity, causing the shunting of blood from veins with an aberrant capillary bed to ...
Andhika Yudistira +2 more
doaj +1 more source