Results 131 to 140 of about 1,120,982 (307)

The prevalence of preoperative anxiety among patients undergoing insertion of penile prosthesis. [PDF]

World J Urol
Hammad FT, Salman MA, Alhammadi A, Afaneh HF, Deyab AF, AlBlooshi S, Askhaita K.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Three-dimensional virtual planning reduces operative time in orthognathic surgery: a procedure-specific retrospective study incorporating additive manufacturing. [PDF]

Oral Maxillofac Surg
Kunisada Y, Yoshioka N, Nishiyama A, Masui M, Kadoya K, Takakura H, Obata K, Ono K, Umemori K, Ibaragi S.   +9 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effect of Orthopedic Resident Surgical Education on Surgical Case Length and Healthcare Costs. [PDF]

J Hand Surg Glob Online
Gomez RW, Valdes KG, Matullo KS.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Implications of cancellation of surgery in a surgery department: a descriptive-exploratory study

Online Brazilian Journal of Nursing
<p class="MsoNormal" style="margin: 0cm 0cm 0pt;"><span style="font-family: ";Arial";,";sans-serif";; font-size: 10pt; mso-ansi-language: EN-US;" lang="EN-US">This descriptive-exploratory study aimed to identify the implications of ...
Willian Morgan, Elizabeth Bernardino, Lillian Daisy Gonçalves Wolff   +2 more
doaj  

Robotic cholecystectomy during surgical training: learning curve and perioperative outcomes of 441 consecutive cases in a high-volume teaching center. [PDF]

J Robot Surg
Gravante G, Mita MT, Altamura A, Barbieri V, Bianco G, Benedicenti S, Catamerò A, Clemente L, Giaracuni G, Grillea G, Leone B, Morelli G, Picciariello A, Puglisi G, Sorge R, Rubichi F, Viola MG.   +16 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Exploratory activity-based direct cost analysis of robotic platforms in urologic surgery. [PDF]

J Robot Surg
Picozzi P, Nocco U, Bossi E, Gattuso D, Labate C, Puleo G, Cimolin V.   +6 more
europepmc   +1 more source