Results 71 to 80 of about 402,902 (267)

„Tworzenie świata” należy rozpocząć od światła. Szkic do portretu Vittorio Storaro na podstawie „Tanga” Carlosa Saury

open access: yesKwartalnik Filmowy, 2001
Esej poświęcony twórczości światowej sławy operatora Vittorio Storaro. Chmielecki analizuje wizualny aspekt Tanga Carlosa Saury. Autor argumentuje, że Storaro reprezentuje postawę, zgodnie z którą rzeczywistość profilmowa okazuje się zbyt uboga, by mogła
Konrad Chmielecki
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Dans les « coulisses » du métier d’opérateur de vidéosurveillance

open access: yesCriminologie, 2013
Pièces maîtresses des dispositifs de vidéosurveillance mis en place dans nombre de villes françaises aujourd’hui, les opérateurs officiant derrière les écrans demeurent pourtant des acteurs de la sécurité dont on sait peu de chose.
Tanguy Le Goff
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A relation between two simple Hardy-Mulholland-type inequalities with parameters

open access: yesJournal of Inequalities and Applications, 2016
By means of weight coefficients and the technique of real analysis, a new Hardy-Mulholland-type inequality with the kernel K λ ( m , n ) : = 1 ln λ U m + ln λ V n + α | ln λ U m − ln λ V n | $$ K_{\lambda}(m,n):=\frac{1}{\ln^{\lambda}U_{m}+\ln^{\lambda ...
Qiang Chen, Yanping Shi, Bicheng Yang
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Information: Concept Clarification and Theoretical Representation

open access: yestripleC: Communication, Capitalism & Critique, 2011
The general theory of information is a synthetic approach, which organizes and encompasses all main directions in information theory. It is developed on three levels: conceptual, methodological and theoretical.
Mark Burgin
doaj   +1 more source

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