Results 161 to 170 of about 2,346,209 (353)
A twenty-first century statistical physics of life [PDF]
The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling molecules involved.
arxiv
A Mathematical Model Accounting for the Organisation in Multiplets of the Genetic Code [PDF]
Requiring stability of genetic code against translation errors, modelised by suitable mathematical operators in the crystal basis model of the genetic code, the main features of the organisation in multiplets of the mitochondrial and of the standard genetic code are explained.
arxiv
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source
Kinetic equation for a gas with attractive forces as a functional equation
Diffusion problems studied in the time scale comparable with time of particles collision lead to kinetic equations which for step-wise potentials are functional equations in the velocity space.
Ryszard Wojnar
doaj
Wigner-Eckart Theorem in the crystal and the organisation of the genetic code [PDF]
Modelising the translation errors by suitable mathematical operators in the crystal basis model of the genetic code and requiring that codons prone to be misread encode the same amino-acid, the main features of the organisation in multiplets of the genetic code are described.
arxiv
Tumor‐informed whole‐genome sequencing (MRD‐EDGESNV) was applied to detect circulating tumor DNA (ctDNA) in patients with colorectal adenomas. Using a 95% specificity threshold, established from stage III colorectal cancer patients, ctDNA was detected in 50% of symptomatic and 25% of asymptomatic adenoma cases with median tumor fractions of 5.9 × 10−5 ...
Amanda Frydendahl+13 more
wiley +1 more source
Asymptotic estimates related to an integro differential equation [PDF]
The paper deals with an integrodifferential operator which models numerous phenomena in superconductivity, in biology and in viscoelasticity. Initialboundary value problems with Neumann, Dirichlet and mixed boundary conditions are analyzed. An asymptotic analysis is achieved proving that for large t, the in uences of the initial data vanish, while the ...
arxiv
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Matrix genetics, part 5: genetic projection operators and direct sums [PDF]
The article is devoted to phenomena of symmetries and algebras in matrix presentations of the genetic code. The Kronecker family of the genetic matrices is investigated, which is based on the alphabetical matrix [C A; U G], where C, A, U, G are the letters of the genetic alphabet. The matrix P=[C A; U G] in the third Kronecker power is the (8*8)-matrix,
arxiv