Results 61 to 70 of about 221,099 (246)

DETECTABILITY OF LINEAR DISCRETE TIME LINEAR SYSTEMS DEFINED BY POSITIVE OPERATORS [PDF]

open access: yesFiabilitate şi Durabilitate, 2010
In this paper we extend the notion of detectability, introduced in [1] in connection with stochastic systems, to a more general class of linear discrete time systems defined by positive operators.
V.M. Ungureanu
doaj  

Matrices defined by frames [PDF]

open access: yesOpuscula Mathematica, 2009
Matrix representations of bounded Hilbert space operators are considered. The matrices in question are defined with respect to frames, rather than bases.
Zbigniew Ambroziński, Krzysztof Rudol
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Some integral operators of Buschman-Erdélyi type

open access: yesRevista Técnica de la Facultad de Ingeniería, 2011
New integral operators involving the generalized Legendre function Pr-n(z) are introduced. Sorne integrals are evaluated.
N. Virchenco
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

A modification of Hardy-Littlewood maximal function on Lie groups [PDF]

open access: yesAUT Journal of Mathematics and Computing
For a real-valued function $f$ on a metric measure space $(X,d,\mu)$ the Hardy-Littlewood centered-ball maximal-function of $f$ is given by the `supremum-norm':$$Mf(x):=\sup_{r>0}\frac{1}{\mu(\mathcal{B}_{x,r})}\int_{\mathcal{B}_{x,r}}|f|d\mu.$$In this ...
Maysam Maysami Sadr
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Novel Method for Solutions of Fourth-Order Fractional Boundary Value Problems

open access: yesFractal and Fractional, 2019
In this paper, we find the solutions of fourth order fractional boundary value problems by using the reproducing kernel Hilbert space method. Firstly, the reproducing kernel Hilbert space method is introduced and then the method is applied to this kind ...
Ali Akgül, Esra Karatas Akgül
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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