Results 61 to 70 of about 458,023 (296)
Corrections are made in this ...
Chen, Mu-Fa, Zhang, Xu
openaire +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Matrices defined by frames [PDF]
Matrix representations of bounded Hilbert space operators are considered. The matrices in question are defined with respect to frames, rather than bases.
Zbigniew Ambroziński, Krzysztof Rudol
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A modification of Hardy-Littlewood maximal function on Lie groups [PDF]
For a real-valued function $f$ on a metric measure space $(X,d,\mu)$ the Hardy-Littlewood centered-ball maximal-function of $f$ is given by the `supremum-norm':$$Mf(x):=\sup_{r>0}\frac{1}{\mu(\mathcal{B}_{x,r})}\int_{\mathcal{B}_{x,r}}|f|d\mu.$$In this ...
Maysam Maysami Sadr
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
DETECTABILITY OF LINEAR DISCRETE TIME LINEAR SYSTEMS DEFINED BY POSITIVE OPERATORS [PDF]
In this paper we extend the notion of detectability, introduced in [1] in connection with stochastic systems, to a more general class of linear discrete time systems defined by positive operators.
V.M. Ungureanu
doaj
A Novel Method for Solutions of Fourth-Order Fractional Boundary Value Problems
In this paper, we find the solutions of fourth order fractional boundary value problems by using the reproducing kernel Hilbert space method. Firstly, the reproducing kernel Hilbert space method is introduced and then the method is applied to this kind ...
Ali Akgül, Esra Karatas Akgül
doaj +1 more source

