Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang +10 more
wiley +2 more sources
<i>In silico</i> and experimental assessment of the 16S-ITS-23S operon as a genetic marker for high-resolution bacterial species identification. [PDF]
Yamakawa AC, Davies M, Gweon HS.
europepmc +1 more source
TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon in <i>Klebsiella oxytoca</i>. [PDF]
Perez C +13 more
europepmc +1 more source
The transcriptional regulator CueR positively regulates the expression of the <i>cueRA</i> operon to maintain copper homeostasis in <i>Pseudomonas chlororaphis</i> zm-1. [PDF]
Wang Z +6 more
europepmc +1 more source
One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler +2 more
wiley +1 more source
Direct bacterial transcript visualization illuminates spatiotemporal environmental adaptation of <i>Mycobacterium tuberculosis</i> in the lung. [PDF]
Lawrence AE, Tan S.
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A standardized gas chromatography–based workflow enables direct functional screening of hydrogenase activity in crude membrane and lysate fractions from native bacteria. Without purification or heterologous expression, hydrogen oxidation is detected across phylogenetically diverse organisms, highlighting the value of activity‐based screening for ...
Marius Stoeckle +2 more
wiley +1 more source
Transcriptional Profiling of Hypo- and Hypervirulent Mycobacterium tuberculosis Isolates Characterised by Differential Expression of the Moa3 Operon. [PDF]
Ambler JM +8 more
europepmc +1 more source
Genome replication and cell division control by the methylation-sensitive GcrA regulator in Agrobacterium tumefaciens. [PDF]
Fournes F +7 more
europepmc +1 more source
A regulator of amino acid catabolism controls Acinetobacter baumannii gut colonization. [PDF]
Geary JH +10 more
europepmc +1 more source

