Results 231 to 240 of about 218,797 (343)

Disrupting Viral Persistence: CRISPR/Cas9‐Based Strategies for Hepatitis B and C Treatment, and Challenges

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Hepatitis B and C viruses (HBV and HCV) remain among the leading causes of liver disease worldwide. Current antiviral drugs, such as nucleotide analogues (NAs), can reduce the replication of new HBV and HCV infections but cannot completely eliminate chronic infections.
Meng‐Fan Li   +3 more
wiley   +1 more source

<i>Chlamydomonas</i> chloroplast genes tolerate compression of the genetic code to just 51 codons. [PDF]

open access: yesProc Natl Acad Sci U S A
Mordaka PM   +6 more
europepmc   +1 more source

Genetic Diversity of Polymyxin Resistance Genes in Klebsiella pneumoniae Clinical Isolates

open access: yesMolecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT This study investigates the genetic diversity and evolutionary mechanisms driving polymyxin resistance in Klebsiella pneumoniae, a critical priority pathogen. By analysing mgrB, phoPQ and pmrAB genes in susceptible (PM‐S) and resistant (PM‐R) populations through neutrality tests (Tajima D, Fu & Li's D) we uncovered polygenic adaptation and ...
Daniel Miceli Serwy   +8 more
wiley   +1 more source

Effects of Lipopolysaccharide Core Modulation on Outer Membrane Protein Function and Virulence in Pectobacterium carotovorum

open access: yesMolecular Plant Pathology, Volume 27, Issue 1, January 2026.
The LPS core is critical for virulence in Pectobacterium carotovorum, as its truncation disrupts outer membrane protein assembly, reducing protease secretion, motility, and soft rot symptoms. ABSTRACT Lipopolysaccharide (LPS) is a critical component of the bacterial outer membrane, which serves as a permeability barrier and site for sensing ...
Yejin Park   +4 more
wiley   +1 more source

Chromosome‐level genome assembly of the photobiont microalga Trebouxia sp. ‘A48’ from the lichen Xanthoria parietina

open access: yesNew Phytologist, Volume 249, Issue 2, Page 1036-1052, January 2026.
Summary Lichens are symbiotic assemblies consisting of multiple organisms, chiefly a fungus and a photosynthetic microorganism, or photobiont. Among diverse photobionts, the most prevalent is the chlorophyte alga Trebouxia. We produced a chromosome‐level assembly of Trebouxia sp. ‘A48’, a photobiont of Xanthoria parietina. The genome was assembled into
Gulnara Tagirdzhanova   +2 more
wiley   +1 more source

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