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Steroidal saponins from the tuber of Ophiopogon japonicus

Steroids, 2012
Eight novel steroidal saponins, ophiopogonins H-O (1-8), along with seven known steroidal saponins (9-15) were isolated from the tubers of Ophiopogon japonicus. The structures of these new compounds were determined by detailed spectroscopic analysis, including extensive 1D and 2D NMR data, and the analysis of hydrolytic reaction products. For the first
Tao, Zhang   +10 more
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Activation of macrophages by the ophiopogon polysaccharide liposome from the root tuber of Ophiopogon japonicus

International Journal of Biological Macromolecules, 2016
This study evaluated the immunomodulatory effects of ophiopogon polysaccharide liposome (OPL) on macrophages in vitro. The phagocytic activity, the secretion of nitric oxide (NO) and inducible nitric oxide synthase (iNOS), the level of cytokines, chemokines and the expression of CD14 and MHC-II costimulatory molecules were measured. Results showed that
Wenjing Sun   +9 more
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Antioxidative and immunological activities of ophiopogon polysaccharide liposome from the root of Ophiopogon japonicus

Carbohydrate Polymers, 2016
The antioxidative and immunoregulatory activities of ophiopogon polysaccharide liposome (OPL) were investigated. The results demonstrated that the radical-scavenging activity increased along with the increasing of OPL concentrations, and the scavenging capability of OPL was slightly stronger than ophiopogon polysaccharide (OP) in vitro. In vivo, OPL at
Yunpeng Fan   +5 more
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Two homoisoflavones from Ophiopogon japonicus

Phytochemistry, 1987
Abstract Two novel homoisoflavones have been isolated from the roots of Ophiopogon japonicus .
Yongxin Zhu, Kedong Yan, Guoshi Tu
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Steroidal glycosides from tubers of Ophiopogon japonicus

Journal of Asian Natural Products Research, 2006
A new steroidal saponin, named ophiopogonin E (1), has been isolated from the tubers of Ophiopogon japonicus, along with five known steroidal saponins (2-6). The structure of the new steroidal glycoside was characterized by spectroscopic analysis and acid-catalyzed hydrolysis as pennogenin 3-O-beta-D-xylopyranosyl (1 --> 4)-beta-D-glucopyranoside (1).
Z-H, Cheng, T, Wu, B-Y, Yu
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Homoisoflavonoids from Ophiopogon japonicus

Helvetica Chimica Acta, 2013
AbstractPhytochemical study on the root tubers of Ophiopogon japonicus resulted in the isolation and identification of 13 homoisoflavonoids, including three new compounds, 8‐formyl‐7‐hydroxy‐5,4′‐dimethoxy‐6‐methylhomoisoflavone (1), 6‐formylisoophiopogonone B (2), and 8‐formylophiopogonanone B (4), and the ten known homoisoflavonoids 3, and 5–13.
Chang‐Xin Zhou   +6 more
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Chemical Components of the Fibrous Root of Ophiopogon japonicus

Chemistry of Natural Compounds, 2014
The rhizome of Ophiopogon japonicus is a well-known traditional Chinese medicine that has been employed as an expectorant, anti-cough medicine, and tonic agent [1]. Previous chemical analyses of the rhizomes of O. japonicus have led to the isolation of several components including steroidal saponins [2–6], homoisoflavonoids [7, 8], a cis-eudesmane ...
Tian Feng   +4 more
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Terpenoid glycosides from Ophiopogon japonicus roots

Phytochemistry, 1990
Abstract The isolation and the structure elucidation of ophiogenin 3- O -α- l -rhamnopyranosyl-(1→2)-β- d -glucopyranoside and bornyl 7- O -α- l -arabinofuranosyl(1→6)-β- d -glucopyranoside through spectral (NMR and FABMS) and chemical study is reported.
ADINOLFI, MATTEO, M. PARRILLI, Y. ZHU
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Determination of Homoisoflavonoids in Ophiopogon japonicus by RP-HPLC

Chromatographia, 2005
The homoisoflavonoid content of 14 samples of Ophiopogon japonicus collected from different parts of China have been investigated. Three principal homoisoflavonoids, methylophiopogonanone A, methylophiopogonanone B, and 6-aldehydo-isoophiopogonanone A, were analyzed simultaneously by reversed-phase high-performance liquid chromatography with a binary ...
Guan Ye   +3 more
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Anti-inflammatory homoisoflavonoids from the tuberous roots of Ophiopogon japonicus

Fitoterapia, 2012
Two new homoisoflavonoids, named ophiopogonone E (1) and ophiopogonanone H (2), together with thirteen known ones (3-15) were isolated from the tuberous roots of Ophiopogon japonicus. Their structures were elucidated by spectroscopic and chemical analyses. Compounds 7 and 15 were isolated from the genus for the first time.
Ning, Li   +5 more
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