The goal of the present study is to develop polymeric matrix films loaded with a combination of free diclofenac sodium (DFSfree) and DFS:Ion exchange resin complexes (DFS:IR) for immediate and sustained release profiles, respectively.
Adelli, Goutham R. +4 more
core +2 more sources
Development of Teleoperated Robotic System for Remote Intraocular Microsurgery
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu +30 more
wiley +1 more source
Susceptibility of conjunctival bacterial pathogens to fluoroquinolones. A comparative study of ciprofloxacin, norfloxacin and ofloxacin [PDF]
In order to determine the most common bacteria implicated in conjunctivitis, and the effectiveness of the antibiotic Fluoroquinolone for its treatment, a total of 50 subjects (100 ) eyes, between the ages of 1-30 years with mean age of 16.94 ± 8.06 years
Faustina, Dr Idu, Odjimogho, Ms Stella
core +1 more source
Usefulness of image guidance in the surgical treatment of petrous apex cholesterol granuloma [PDF]
The petrous apex is a pyramid-shaped structure, located medial to the inner ear and the intrapetrous segment of the internal carotid artery. Lesions of the petrous apex can be surgically treated through different surgical routes. Because of the important
A. Pietrantonio +5 more
core +3 more sources
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo +16 more
wiley +1 more source
Applications of deep learning for detecting ophthalmic diseases with ultrawide-field fundus images [PDF]
AIM: To summarize the application of deep learning in detecting ophthalmic disease with ultrawide-field fundus images and analyze the advantages, limitations, and possible solutions common to all tasks.
Qing-Qing Tang +4 more
doaj +1 more source
Terahertz-based system for dehydration analysis of hydrogel contact lenses [PDF]
The use of terahertz-based techniques has grown very fast since they are capable of performingevaluations at molecular level, being very suitable for the analysis of biological samples and bioma-terials such as those for contact lenses.
Burgos Fernández, Francisco Javier +3 more
core +2 more sources
Response to ‘Comment on: ‘A randomized masked pilot clinical trial to compare the efficacy of topical 1% Voriconazole ophthalmic solution as monotherapy to combination therapy with topical 0.02% Polyhexamethylene biguanide and 0.02% Chlorhexidine in the treatment of Acanthamoeba keratitis’’ [PDF]
Bhupesh Bagga +6 more
openalex +1 more source
This study investigates the role of PACS‐2 in IDD, demonstrating that it suppresses the nuclear translocation of SP1, thereby downregulating its downstream target LRRK2. This reduces LRRK2‐mediated ubiquitination and degradation of Mfn2 through the JNK pathway, preserving MAM integrity and promoting NPSC survival.
Liang Kang +19 more
wiley +1 more source
Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho +5 more
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