Results 121 to 130 of about 698,290 (348)

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Study of Macular Microvascular Changes in Patients with Symptomatic Lacunar Cerebral Infarction Using Viaoptical Coherence Tomography Angiography (OCTA)

International Journal of General Medicine
Meishuang Li,1– 4,* Huiyu Xi,1,3,4,* Rongrong Guan,5,* Yalu Liu,1,3,4 Lina Guan,1,3,4 Dandan Zong,1,4,6 Nuan Wang,1,4 Haiyang Liu1,3,4 1Department of Ophthalmology, Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University,
Li M, Xi H, Guan R, Liu Y, Guan L, Zong D, Wang N, Liu H   +7 more
doaj  

Subthreshold Nanosecond Laser, from Trials to Real-Life Clinical Practice: A Cohort Study

Clinical Ophthalmology, 2021
Hasan Chichan,1,2 Matthias Maus,2,* Ludwig M Heindl1,3,* 1Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, 50923, Germany; 2Sehkraft Eye Center, Cologne, 50667, Germany; 3Center for ...
Chichan H, Maus M, Heindl LM
doaj  

Large language models approach expert-level clinical knowledge and reasoning in ophthalmology: A head-to-head cross-sectional study [PDF]

, 2023
Arun James Thirunavukarasu, Shathar Mahmood, Andrew Malem, William Foster, Rohan Sanghera, Refaat Hassan, Sean X. Zhou, Shiao Wei Wong, Yee Ling Wong, Yu Jeat Chong, Abdullah Shakeel, Yin‐Hsi Chang, Benjamin Kye Jyn Tan, Nikhil Jain, Ting Fang Tan, Saaeha Rauz, Daniel Shu Wei Ting, Darren Shu Jeng Ting   +17 more
openalex   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Influencing Factors of Self-Management Behavior in Patients with Glaucoma in West China: A Cross-Sectional Study

Patient Preference and Adherence
Xin Zhang, Jie Ren, Li Tang, Ji-Hong Zeng, Jing Tang Department of Ophthalmology, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, Sichuan Province, 610041, People’s Republic of China.Correspondence: Jing
Zhang X, Ren J, Tang L, Zeng JH, Tang J
doaj  

Gender-based differences in letters of recommendation written for ophthalmology residency applicants. [PDF]

, 2019
BACKGROUND:To determine whether gender-based differences may be present in letters of recommendation written for ophthalmology residency applicants. METHODS:All applications submitted through SF Match to the UCLA Stein Eye Institute Residency Training ...
Gordon, Lynn K, Lin, Fei, Oh, Soo Kyung, Pineles, Stacy L, Rosenberg, Jamie B, Tsui, Irena   +5 more
core  

Large language models and their impact in ophthalmology.

The Lancet Digital Health, 2023
B. Betzler, Haichao Chen, Ching-Yu Cheng, Cecilia S. Lee, Guochen Ning, Su Jeong Song, Aaron Y. Lee, Ryo Kawasaki, Peter van Wijngaarden, Andrzej Grzybowski, Mingguang He, Dawei Li, An Ran Ran, D. Ting, K. Teo, Paisan Ruamviboonsuk, S. Sivaprasad, V. Chaudhary, R. Tadayoni, Xiaofei Wang, C. Y. Cheung, Yingfeng Zheng, Ya Xing Wang, Y. Tham, T. Y. Wong   +24 more
semanticscholar   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) Consensus Regarding the Preferred Treatment for Demodex Blepharitis

Clinical Ophthalmology
Eric Donnenfeld,1 Kelly K Nichols,2 Brandon D Ayres,3 Marjan Farid,4 Preeya K Gupta,5,6 Richard Lyndon Lindstrom,7 Stephen Pflugfelder,8 Christopher E Starr,9 Nandini Venkateswaran,10 Ian Benjamin Gaddie,11 Paul M Karpecki,12 Cecelia Koetting,13 Selina ...
Donnenfeld E, Nichols KK, Ayres BD, Farid M, Gupta PK, Lindstrom RL, Pflugfelder S, Starr CE, Venkateswaran N, Gaddie IB, Karpecki PM, Koetting C, McGee S, Periman LM, Yeu E   +14 more
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