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Treatment of Graves’ ophthalmopathy

Medicina Clínica (English Edition), 2021
Graves' ophthalmopathy is an inflammatory disease with primary involvement of the extraocular muscles and the orbit. It encompasses the most common extra-thyroid manifestation in patients with Graves-Basedow disease. The underlying cause is molecular mimicry with the TSH receptor in ocular fibroblasts, leading to an immuno-mediated pathogenesis ...
Andrés, González-García   +1 more
openaire   +2 more sources

Radioiodine and thyroid-associated ophthalmopathy

open access: yesOrbit, 1996
Particular attention has recently been paid to the relationship between radioiodine administration and the course of thyroid-associated ophthalmopathy (TAO).
Fausto Bogazzi   +2 more
exaly   +2 more sources

Thyroid ophthalmopathy

Current Opinion in Ophthalmology, 1994
Thyroid ophthalmopathy, idiopathic orbital inflammation, and orbital infection can occasionally demonstrate overlapping clinical features. It is essential to distinguish between these processes because appropriate treatments are distinct in each case.
E G, Faktorich, N, Tucker, J M, O'Brien
openaire   +2 more sources

IgG4-related ophthalmopathy

Arkhiv patologii, 2022
IgG4-related disease is a chronic inflammatory fibrosing disease of unknown etiology, characterized by the presence of volumetric lesions that can clinically simulate malignant tumors, a pronounced IgG4-positive lymphoplasmacytic infiltrate, and an increase in the level of IgG4 in the blood serum.
S.G. Radenska-Lopovok   +3 more
openaire   +2 more sources

Hashimoto’s Ophthalmopathy

The American Journal of the Medical Sciences, 2011
The authors reported 2 cases of Hashimoto's ophthalmopathy. These cases presented with no preceding illness; euthyroid state; acute presentation of painful or painless ophthalmoplegia, preferentially affecting the lateral rectus muscles; positive antithyroglobulin/antithyroid peroxidase antibodies and good responses to steroid treatment.
Fuyuki, Tateno   +3 more
openaire   +2 more sources

IMMUNOGENETICS OF GRAVES' OPHTHALMOPATHY

Clinical Endocrinology, 1988
SUMMARYWe have performed an immunogenetic analysis of 53 patients with severe Graves' ophthalmopathy, 51 patients with Graves' disease but little or no clinically apparent eye disease, and 90 controls. The distribution of restriction fragment length polymorphisms was analysed in the three groups, using probes for the HLA‐DQα and DRβ regions, the T‐cell
A P, Weetman   +5 more
openaire   +2 more sources

Graves ophthalmopathy

Current Opinion in Ophthalmology, 2001
Graves ophthalmopathy (GO) is an autoimmune disease that typically affects the thyroid gland and the orbit. The roles of the thyroid stimulating hormone receptor and cellular and humoral immunity in the pathogenesis of GO are being investigated. Investigators are gaining insights into the epidemiology of GO as it relates to other ocular and autoimmune ...
openaire   +2 more sources

Postpartum Proptosis with Ophthalmopathy

Optometry and Vision Science, 2001
Background. Postpartum thyroid disease presents in two forms: postpartum thyroiditis (PPT) and postpartum Graves’ disease (PPGD). Case Report. A case of postpartum thyroid dysfunction with ophthalmopathy is presented.
H F, Ford, A, Spies
openaire   +2 more sources

The Ophthalmopathy of Graves' Disease

Annual Review of Medicine, 1992
Ophthalmopathy is an integral component of Graves’ disease. It usually appears at the same time as hyperthyroidism, and is characterized by proptosis (exophthalmos), periorbital and conjunctival edema, eye muscle dysfunction, and on occasion corneal ulceration or optic neuropathy.
J A, Carter, R D, Utiger
openaire   +2 more sources

Graves' ophthalmopathy

Medical Clinics of North America, 1995
Graves' ophthalmopathy is an organ-specific autoimmune process strongly linked to Graves' hyperthyroidism. Although the hyperthyroidism can be successfully treated, it is often the ophthalmopathy that produces the greatest long-term disability for patients suffering from this disease.
openaire   +2 more sources

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