Opiate substitution treatment and HIV transmission in people who inject drugs: systematic review and meta-analysis. [PDF]
To quantify the effect of opiate substitution treatment in relation to HIV transmission among people who inject drugs.Systematic review and meta-analysis of prospective published and unpublished observational studies.Search of Medline, Embase, PsychINFO, and the Cochrane Library from the earliest year to 2011 without language restriction.We selected ...
MacArthur GJ+7 more
europepmc +8 more sources
Introduction: Use of intravenous heroin carries a risk of serious medical conditions, including acquiring blood-borne infections. Therefore, hepatitis B virus (HBV) and hepatitis C virus (HCV) infection represent a threat for people who inject drugs ...
Sinisa Skocibusic+7 more
doaj +5 more sources
A National Study of the Retention of Irish Opiate Users in Methadone Substitution Treatment [PDF]
Retention in treatment is a key indicator of methadone treatment success. The study aims to identify factors that are associated with retention.To determine retention in treatment at 12 months for Irish opiate users in methadone substitution treatment and to indicate factors that increase the likelihood of retention.National cohort study of randomly ...
Jean Long+6 more
openaire +4 more sources
Combination interventions to prevent HCV transmission among people who inject drugs: modelling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy [PDF]
BackgroundInterventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis C virus (HCV) prevalence among people who inject drugs (PWID).
Aspinall+32 more
core +5 more sources
Attentional bias and treatment adherence in substitute-prescribed opiate users [PDF]
Attentional bias (AB) is implicated in the development and maintenance of substance dependence and in treatment outcome. We assessed the effects of attentional bias modification (ABM), and the relationship between AB and treatment adherence in opiate dependent patients.An independent groups design was used to compare 23 opiate dependent patients with ...
Charles, M+5 more
openaire +7 more sources
Outcome of heroin-dependent adolescents presenting for opiate substitution treatment [PDF]
Because the outcome of methadone and buprenorphine substitution treatment in adolescents is unclear, we completed a retrospective cohort study of 100 consecutive heroin-dependent adolescents who sought these treatments over an 8-year recruitment period. The participants' average age was 16.6 years, and 54 were female. Half of the patient group remained
Kathy Kernan, John Fagan, Bobby P Smyth
openaire +4 more sources
The newer opioid agonist treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older harm reduction treatment [PDF]
Background: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold ...
Bacciardi, Silvia+8 more
core +3 more sources
Effects of opiate substitution treatment on mortality for opioids users: a systematic review and meta-analysis [PDF]
Abstract Background Opioid dependence is associated with high risk of premature death. Opiate-substitution treatment (OST) is the major treatment in community for opioid dependence worldwide. We aimed to estimate crude mortality rates (CMRs) and the effects of OST on mortality risk by meta-analysis.
Mo-Xuan Liu+7 more
openaire +3 more sources
How to overcome hurdles in opiate substitution treatment? A qualitative study with general practitioners in Belgium [PDF]
Opiate substitution treatment (OST) is the administration of opioids (methadone or buprenorphine) under medical supervision for opiate addiction. Several studies indicate a large unmet need for OST in general practice in Antwerp, Belgium. Some hurdles remain before GPs engage in OST prescribing.Formulate recommendations to increase engagement of GPs in
Fraeyman, Jessica+4 more
openaire +4 more sources
Mobile telephone contingency management to encourage adherence to supervised medication among individuals most at risk of non-adherence to opioid agonist treatment: a study protocol for a feasibility study (TIES2) [PDF]
Background Supervision of opioid agonist treatment (OAT) ensures that individuals take their correct daily dose to minimise withdrawal and craving, safeguard against diversion and overdose, and receive optimal benefit from OAT. There is an urgent need to
Nicola Metrebian+7 more
doaj +2 more sources