Results 11 to 20 of about 133,922 (249)

How to overcome hurdles in opiate substitution treatment? A qualitative study with general practitioners in Belgium [PDF]

open access: goldEuropean Journal of General Practice, 2016
Opiate substitution treatment (OST) is the administration of opioids (methadone or buprenorphine) under medical supervision for opiate addiction. Several studies indicate a large unmet need for OST in general practice in Antwerp, Belgium. Some hurdles remain before GPs engage in OST prescribing.Formulate recommendations to increase engagement of GPs in
Jessica Fraeyman   +4 more
semanticscholar   +5 more sources

Effects of opiate substitution treatment on mortality for opioids users: a systematic review and meta-analysis [PDF]

open access: bronzeThe Lancet, 2017
Abstract Background Opioid dependence is associated with high risk of premature death. Opiate-substitution treatment (OST) is the major treatment in community for opioid dependence worldwide. We aimed to estimate crude mortality rates (CMRs) and the effects of OST on mortality risk by meta-analysis.
Jun Ma   +6 more
semanticscholar   +4 more sources

Psychosocial interventions in opiate substitution treatment services: does the evidence provide a case for optimism or nihilism? [PDF]

open access: greenAddiction, 2017
Clinical guidelines from around the world recommend the delivery of psychosocial interventions as part of routine care in opiate substitution treatment (OST) programmes. However, although individual studies demonstrate benefit for structured psychosocial interventions, meta-analytical reviews find no benefit for manual-based treatments beyond 'routine ...
Ed Day, Luke Mitcheson
semanticscholar   +7 more sources

Outcome of heroin-dependent adolescents presenting for opiate substitution treatment [PDF]

open access: greenJournal of Substance Abuse Treatment, 2011
Because the outcome of methadone and buprenorphine substitution treatment in adolescents is unclear, we completed a retrospective cohort study of 100 consecutive heroin-dependent adolescents who sought these treatments over an 8-year recruitment period. The participants' average age was 16.6 years, and 54 were female. Half of the patient group remained
Bobby P. Smyth, John Fagan, Kathy Kernan
semanticscholar   +5 more sources

Treatment satisfaction and quality of support in outpatient substitution treatment: opiate users’ experiences and perspectives [PDF]

open access: greenDrugs: Education, Prevention and Policy, 2014
AbstractAims: Patient-reported outcomes have become an important source of information to guide service provision. Although opiate substitution treatment (OST) is an evidence-based and widely available intervention for opiate dependent individuals, evaluation studies have primarily focused on objective outcome indicators rather than on clients ...
Wouter Vanderplasschen   +3 more
semanticscholar   +5 more sources

Pilot study of a social network intervention for heroin users in opiate substitution treatment: study protocol for a randomized controlled trial. [PDF]

open access: goldTrials, 2013
BackgroundResearch indicates that 3% of people receiving opiate substitution treatment (OST) in the UK manage to achieve abstinence from all prescribed and illicit drugs within 3 years of commencing treatment, and there is concern that treatment services
Day E   +9 more
europepmc   +4 more sources

A National Study of the Retention of Irish Opiate Users in Methadone Substitution Treatment [PDF]

open access: greenThe American Journal of Drug and Alcohol Abuse, 2012
Retention in treatment is a key indicator of methadone treatment success. The study aims to identify factors that are associated with retention.To determine retention in treatment at 12 months for Irish opiate users in methadone substitution treatment and to indicate factors that increase the likelihood of retention.National cohort study of randomly ...
Louise Mullen   +6 more
openalex   +4 more sources

Attentional bias and treatment adherence in substitute-prescribed opiate users [PDF]

open access: greenAddictive Behaviors, 2015
Attentional bias (AB) is implicated in the development and maintenance of substance dependence and in treatment outcome. We assessed the effects of attentional bias modification (ABM), and the relationship between AB and treatment adherence in opiate dependent patients.An independent groups design was used to compare 23 opiate dependent patients with ...
Matthew Charles   +5 more
openalex   +7 more sources

Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy [PDF]

open access: hybrid, 2013
BackgroundInterventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis C virus (HCV) prevalence among people who inject drugs (PWID).
Natasha K. Martin   +4 more
openalex   +6 more sources

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