Results 11 to 20 of about 15,739 (221)

Outcome of heroin-dependent adolescents presenting for opiate substitution treatment [PDF]

open access: yesJournal of Substance Abuse Treatment, 2012
Because the outcome of methadone and buprenorphine substitution treatment in adolescents is unclear, we completed a retrospective cohort study of 100 consecutive heroin-dependent adolescents who sought these treatments over an 8-year recruitment period. The participants' average age was 16.6 years, and 54 were female. Half of the patient group remained
Smyth, Bobby P   +2 more
openaire   +5 more sources

The impact of opiate substitution treatment on mortality risk in drug addicts: a natural experiment study

open access: yesHealth Services and Delivery Research, 2019
Background: Opiate substitution treatment (OST) is the main treatment for people addicted to heroin and other opioid drugs. However, there is limited information on how the delivery of this treatment affects mortality risk. Objectives: To investigate the
Colin D Steer   +10 more
doaj   +2 more sources

A pilot feasibility randomised controlled trial of an adjunct brief social network intervention in opiate substitution treatment services [PDF]

open access: yesBMC Psychiatry, 2018
Background Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three years of commencing treatment.
Ed Day   +12 more
doaj   +2 more sources

A National Study of the Retention of Irish Opiate Users in Methadone Substitution Treatment [PDF]

open access: yesThe American Journal of Drug and Alcohol Abuse, 2012
Retention in treatment is a key indicator of methadone treatment success. The study aims to identify factors that are associated with retention.To determine retention in treatment at 12 months for Irish opiate users in methadone substitution treatment and to indicate factors that increase the likelihood of retention.National cohort study of randomly ...
Mullen, Louise   +6 more
openaire   +5 more sources

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review [PDF]

open access: yesAddiction, Volume 121, Issue 5, Page 1083-1099, May 2026.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +2 more sources

FORWARDS-1: an adaptive, single-blind, placebo-controlled ascending dose study of acute baclofen on safety parameters in opioid dependence during methadone-maintenance treatment—a pharmacokinetic-pharmacodynamic study

open access: yesTrials, 2022
Background Treatment of opiate addiction with opiate substitution treatment (e.g. methadone) is beneficial. However, some individuals desire or would benefit from abstinence but there are limited options to attenuate problems with opiate withdrawal ...
L. M. Paterson   +8 more
doaj   +1 more source

Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine

open access: yesFrontiers in Psychiatry, 2020
BackgroundOpiate addiction is a major health problem in many countries. A crucial component of the medical treatment is the management of highly aversive opiate withdrawal signs, which may otherwise lead to resumption of drug taking.
Rahimah Hassan   +6 more
doaj   +1 more source

Differences in depression severity and frequency of relapses in opiate addicts treated with methadone or opiate blocker after detoxification [PDF]

open access: yesVojnosanitetski Pregled, 2012
Background/Aim. Relapse of opiate dependence is a common occurrence after detoxification and introduction of opiate addicts in abstinence from opiates. Clinical evaluation showed that over 90% of opiate addicts exhibit depressive manifestations during
Jovanović Tatjana   +2 more
doaj   +1 more source

Attentional bias and treatment adherence in substitute-prescribed opiate users [PDF]

open access: yesAddictive Behaviors, 2015
Attentional bias (AB) is implicated in the development and maintenance of substance dependence and in treatment outcome. We assessed the effects of attentional bias modification (ABM), and the relationship between AB and treatment adherence in opiate dependent patients.An independent groups design was used to compare 23 opiate dependent patients with ...
Charles, M   +5 more
openaire   +5 more sources

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