Results 181 to 190 of about 593,453 (414)

Persistent Opioid Use Among Pediatric Patients After Surgery

Pediatrics, 2018
Through a national sample of adolescents and young adults, we investigated the incidence of persistent opioid use after common pediatric surgeries. BACKGROUND: Despite efforts to reduce nonmedical opioid misuse, little is known about the development of ...
C. Harbaugh, J. Lee, Hsou-Mei Hu, S. McCabe, T. Voepel-Lewis, M. Englesbe, C. Brummett, J. Waljee   +7 more
semanticscholar   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Policies, adaptations, and ongoing challenges to naloxone, buprenorphine and nonprescription syringe access across four-states: Findings from an environmental scan and key informant interviews

Drug and Alcohol Dependence Reports
Background: As the US opioid-involved morbidity and mortality increase, uptake and implementation of evidence-based interventions remain key policy responses.
Anthony S. Floyd, Joseph Silcox, Gail Strickler, Thuong Nong, Malcolm Blough, Derek Bolivar, Megan Rabin, Jeffrey Bratberg, Adriane N. Irwin, Daniel M. Hartung, Ryan N. Hansen, Robert Bohler, Traci C. Green   +12 more
doaj  

Patient Perspectives of Disease Activity, Medications and Substance Use in People with Fibromyalgia

Open Access Rheumatology: Research and Reviews, 2022
Thomas Khoo,1 Catherine L Hill,1– 3 Elizabeth Hoon,4,5 Samuel Whittle1 1Rheumatology Unit, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia; 2Rheumatology Unit, The Royal Adelaide Hospital, Adelaide, South Australia, Australia ...
Khoo T, Hill CL, Hoon E, Whittle S
doaj  

Machine Learning Harnesses Molecular Dynamics to Discover New $μ$ Opioid Chemotypes [PDF]

arXiv, 2018
Computational chemists typically assay drug candidates by virtually screening compounds against crystal structures of a protein despite the fact that some targets, like the $\mu$ Opioid Receptor and other members of the GPCR family, traverse many non-crystallographic states.
arxiv  

Variation in the infant health effects of the women, infants, and children program by predicted risk using novel machine learning methods

Health Economics, Volume 32, Issue 1, Page 194-217, January 2023., 2023
Abstract The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) has an extensive literature documenting positive effects on infant health outcomes, specifically preterm birth, low birthweight, small size for gestational age, and infant mortality.
Evan D. Peet, Dana Schultz, Susan Lovejoy, Fuchiang (Rich) Tsui   +3 more
wiley   +1 more source

Differential behaviour of LPH‐(61–91)‐peptide in different model systems: Comparison of the opioid activities of LPH‐(61–91)‐peptide and its fragments [PDF]

, 1977
András Z. Rónai, László Gráf, József I. Székely, Zsuzsa Dunai-Kovàcs, S. Bajusz   +4 more
openalex   +1 more source

Optimizing Peripheral Nerve Block Placement in Hip Surgery: A Cadaveric Study Mapping the Posterior Cutaneous Innervation

Clinical Anatomy, EarlyView.
ABSTRACT Optimizing analgesia after hip surgery enables more rapid recovery. However, peripheral nerve blocks (PNBs) often fail to provide adequate pain relief in the posterolateral hip as they typically target the lateral cutaneous nerve of the thigh (LCNT).
Ziki Gurney, Kenneth Saw Kai Wei, Leia Boote, Daniel Gareth Stolady, Benjamin Fox, Alan R. Norrish   +5 more
wiley   +1 more source

CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications

Pharmacogenomics and Personalized Medicine, 2017
Jennifer L St Sauver,1,2 Janet E Olson,1,3 Veronique L Roger,1,2,4 Wayne T Nicholson,5 John L Black III,3,6 Paul Y Takahashi,7 Pedro J Caraballo,7 Elizabeth J Bell,2 Debra J Jacobson,1,2 Nicholas B Larson,1 Suzette J Bielinski,1,3 1Department of Health ...
St Sauver JL, Olson JE, Roger VL, Nicholson WT, Black III JL, Takahashi PY, Caraballo PJ, Bell EJ, Jacobson DJ, Larson NB, Bielinski SJ   +10 more
doaj  

A Prospective Evaluation of Opioid Utilization After Upper-Extremity Surgical Procedures: Identifying Consumption Patterns and Determining Prescribing Guidelines. [PDF]

, 2016
BACKGROUND: Although adequate management of postoperative pain with oral analgesics is an important aspect of surgical procedures, inadvertent overprescribing can lead to excess availability of opioids in the community for potential diversion.
Abboudi, Jack, Ilyas, Asif M, Jones, Christopher M., Kim, Nayoung, Kirkpatrick, William, Leinberry, Charles, Liss, Frederic, Lutsky, Kevin F F., Maltenfort, Mitchell, Matzon, Jonas L., Wang, Mark L.   +10 more
core   +1 more source