Results 191 to 200 of about 495,046 (363)

A Study on the Addictive Feature of Nonsuicidal Self‐Injury in Adolescents With Depression Disorders and Its Correlation With Serum Beta‐Endorphin Concentration and Neural Reward Responsiveness

open access: yesiRADIOLOGY, EarlyView.
NSSI is addictive in adolescents with depression disorders. It may be related to the decrease of serum beta‐endorphin concentration and the activation of brain reward system. ABSTRACT Background Nonsuicidal self‐injury (NSSI) in adolescents with depression disorders often exhibits addictive patterns, potentially linked to serum beta‐endorphin levels ...
Jie Li   +6 more
wiley   +1 more source

Effects of streptozotocin-induced diabetes on feeding stimulated by centrally administered opioid agonists

open access: green, 1989
Blake A. Gosnell   +3 more
openalex   +1 more source

Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Purpose Pain, sleep disturbances, and substance use are common in adolescence, with research indicating that genetic and environmental factors account for variation in each of these behavioral and health outcomes. Moreover, pain, sleep disturbances, and substance use often co‐occur during adolescence. However, research has not examined whether
Kit K. Elam   +4 more
wiley   +1 more source

N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro10]dynorphin A(1–11) [PDF]

open access: green, 1988
Jean Edouard Gairin   +5 more
openalex   +1 more source

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu   +11 more
wiley   +1 more source

Challenges in opioid therapy implementation: national survey of palliative care consultation services. [PDF]

open access: yesBMC Palliat Care
Mueller E   +5 more
europepmc   +1 more source

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano   +4 more
wiley   +1 more source

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