Results 251 to 260 of about 258,746 (296)

A Comprehensive Narrative Review of Protonitazene: Pharmacological Characteristics, Detection Techniques, and Toxicology. [PDF]

Basic Clin Pharmacol Toxicol
Verbeek J, Brinkman DJ.
europepmc   +1 more source

Homeostatic scaling of dynorphin signaling by a non-canonical opioid receptor. [PDF]

Nat Commun
Li X, Winters ND, Pandey S, Lankford C, Stoveken HM, Smith E, Chang CT, Zucca S, Scampavia L, Spicer T, Martemyanov KA.   +10 more
europepmc   +1 more source

Cannabis Use in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Reasons for Use. [PDF]

Brain Sci
Backmund M, Zámbó GG, Schöfl S, Soyka M.   +3 more
europepmc   +1 more source

An Advanced Practice Nurse's Contributions to the Care of Opioid-Dependent Patients in an Acute Somatic Hospital: A Qualitative Study. [PDF]

Scand J Caring Sci
Schneider K, Grossmann F, Jaiteh C, Knüppel Lauener S.   +3 more
europepmc   +1 more source

Positive Emotion Dysregulation in Opioid Use Disorder and Normalization by Mindfulness-Oriented Recovery Enhancement: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Psychiatry
Garland EL, Hudak J, Hanley AW, Bernat E, Froeliger B.   +4 more
europepmc   +1 more source

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Opioids

Surgical Neurology, 2007
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (
C, Zöllner, C, Stein
openaire   +4 more sources

Opioid mechanisms and opioid drugs

Anaesthesia & Intensive Care Medicine, 2008
Abstract The opioid system comprises four receptor subtypes: μ (MOP), κ (KOP), δ (DOP) (i.e. the so-called ‘classical' opioid receptors) and the more recently identified nociceptin/orphanin FQ peptide (N/OFQ) receptor (NOP). Selective endogenous peptides, typically cleaved from larger precursor proteins, have been identified for all subtypes.
McDonald, J, Lambert, DG
openaire   +4 more sources

Opioid and non-opioid analgesics

Best Practice & Research Clinical Anaesthesiology, 2003
Opioids are the most potent analgesics. Toxicity results either from effects mediated by variation in affinity and intrinsic efficacy at specific opioid receptors or, rarely, from a direct toxic effect of the drugs. For some adverse effects, opioids exhibit a 'dual pharmacology' whereby these effects are usually observed only in pain-free individuals ...
Gail Gillespie, Stephan A. Schug, William Robert Garrett   +2 more
openaire   +3 more sources