Results 271 to 280 of about 593,453 (414)

Nucleus accumbens shell electrical lesion attenuates seizures and gliosis in chronic temporal lobe epilepsy rats

Epileptic Disorders, EarlyView.
Abstract Objective Temporal lobe epilepsy (TLE) is the most prevalent form of epilepsy. Prior research has indicated the involvement of the nucleus accumbens shell (NAcSh) in the process of epileptogenesis, thereby implying its potential as a therapeutic target for TLE.
Shuaishuai Xue, Peiyao Yi, Yangqi Mao, Zhengming Zhan, Yonghua Cai, Zibin Song, Kewan Wang, Kaijun Yang, Ye Song, Xingqin Wang, Hao Long   +10 more
wiley   +1 more source

Controlled Substance Prescribing Patterns Among Fatal Overdose Decedents with an Opioid, Stimulant, or Both Contributing to Death - Pennsylvania, 2017-2022. [PDF]

MMWR Morb Mortal Wkly Rep
Hayden S, Murzynski SM, Bolton A, Goetz CT.   +3 more
europepmc   +1 more source

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

Exploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang, Yue Yin, Huaijuan Zhou, Bowen Chi, Ling Guan, Pei Li, Jinhua Li, Yilong Wang   +7 more
wiley   +1 more source

Teens and opioids postsurgery (TOPS): protocol for a prospective observational study describing associations between sleep deficiency and opioid use following outpatient surgery in adolescents. [PDF]

BMJ Open
Groenewald CB, Palermo T, Rabbitts JA, Flack RL, Kreider SL.   +4 more
europepmc   +1 more source

Similarity between μ‐opioid receptors in mouse vas deferens and guinea‐pig ileum

, 1985
Jacqueline Goodall, I E Hughes, Dennis Mackay   +2 more
openalex   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

Editorial: Understanding and managing diabetic neuropathy: current perspectives and future directions

Frontiers in Neuroscience
Paramita Basu, Pranav Prasoon, Keiichiro Susuki   +2 more
doaj   +1 more source

Improving Multimodal Analgesic Use After Otolaryngologic Surgery-A Single-Institution Experience of 9000 Patients. [PDF]

OTO Open
Plonowska-Hirschfeld KA, Saroya J, Herrera J, Chang JL, Goldberg AN, Seth R, Durr ML.   +6 more
europepmc   +1 more source

Differential ontogeny of multiple opioid receptors (mu, delta, and kappa) [PDF]

, 1985
J W Spain, BL Roth, CJ Coscia
openalex   +1 more source

Organ‐on‐Chip: The Future of Nutrition Research in a One Health World

Food Frontiers, EarlyView.
Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta, Maria Elexpuru‐Zabaleta, Sandra Sumalla Cano, Yasmany Armas Diaz, Francesca Giampieri, Zou Xiaobo, Di Zhang, Giuseppe Grosso, Maurizio Battino   +8 more
wiley   +1 more source