Results 381 to 390 of about 593,453 (414)
Some of the next articles are maybe not open access.
Opioid and anti‐opioid peptides
Fundamental & Clinical Pharmacology, 1995Summary— The numerous endogenous opioid peptides (β‐endorphin, enkephalins, dynorphins…) and the exogenous opioids (such as morphine) exert their effects through the activation of receptors belonging to four main types: μ, Δ, k and ε. Opioidergic neurones and opioid receptors are largely distributed centrally and peripherally. It is thus not surprising
openaire +3 more sources
Neurologic Clinics, 1993
The major clinical uses for opioids are to control pain, suppress cough, and to treat diarrhea. These drugs, however, have the potential for abuse. It is postulated that the significant mood-altering effects of opioids combined with their pharmacology, in which tolerance and physical and psychological dependence occur, account for their abuse liability.
openaire +2 more sources
The major clinical uses for opioids are to control pain, suppress cough, and to treat diarrhea. These drugs, however, have the potential for abuse. It is postulated that the significant mood-altering effects of opioids combined with their pharmacology, in which tolerance and physical and psychological dependence occur, account for their abuse liability.
openaire +2 more sources
Non-opioid actions of opioid peptides
Life Sciences, 2004Beside the well known actions of opioid peptides on mu-, delta- and kappa-opioid receptors, increasing amount of pharmacological and biochemical evidence has recently been published about non-opioid actions of various opioid peptides. These effects are not abolished by naloxone treatments.
Maria Wollemann, Sándor Benyhe
openaire +3 more sources
Wide Variation and Excessive Dosage of Opioid Prescriptions for Common General Surgical Procedures
Annals of Surgery, 2017Objective: To examine opioid prescribing patterns after general surgery procedures and to estimate an ideal number of pills to prescribe. Background: Diversion of prescription opioids is a major contributor to the rising mortality from opioid overdoses ...
M. Hill +3 more
semanticscholar +1 more source
Opioid receptors and endogenous opioid peptides [PDF]
Medicinal Research Reviews, 1991 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire +2 more sources
1984
Publisher Summary Opioid peptides are endogenous or synthetic peptides characterized by a spectrum of pharmacological activity similar to that of morphine and other narcotic agonist drugs. This chapter describes the psychobiology of opiates by analyzing their neurochemical correlates at the brain level and the role of different receptor sites.
OLIVERIO, Alberto +2 more
openaire +4 more sources
Publisher Summary Opioid peptides are endogenous or synthetic peptides characterized by a spectrum of pharmacological activity similar to that of morphine and other narcotic agonist drugs. This chapter describes the psychobiology of opiates by analyzing their neurochemical correlates at the brain level and the role of different receptor sites.
OLIVERIO, Alberto +2 more
openaire +4 more sources
Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2019Abstract Opioids are effective in acute and cancer pain management and have increasingly been prescribed in chronic non-cancer pain despite concerns regarding long-term use and lack of efficacy. Opioid actions are via G protein coupled receptors, the activation of which leads to a variety of physiological consequences including analgesia. Prescribing
Helen Laycock, Carston Bantel
openaire +2 more sources
Opioids, opioid receptors, and the immune response
Drug and Alcohol Dependence, 2001It is now clear that opioid receptors participate in the function of the cells of the immune system, and evidence suggests that opioids modulate both innate and acquired immune responses. We review literature here which establishes that mu-, kappa-, and delta-opioid compounds alter resistance to a variety of infectious agents, including the Human ...
Lois McCarthy +4 more
openaire +3 more sources
Opioids and Opioid Receptors in Peripheral Tissues
Scandinavian Journal of Gastroenterology, 1987Opioid peptides belonging to the enkephalin, beta-endorphin or dynorphin family, acting on specific opiate receptors may be found in peripheral tissues. Enkephalins have a widespread peripheral distribution, while beta-endorphin and dynorphin may be found locally in the enteric nervous system.
Thomas Hedner, Jean Cassuto
openaire +2 more sources
Opioid genetics in the context of opioid switching
Current Opinion in Supportive & Palliative Care, 2012On a population level, there is no difference in terms of efficacy or side-effects between any of the strong opioids. On an individual level, however, there is marked variation in response to opioids. This review presents some of the recent advances in opioid pharmacogenetic studies.A growing number of genes have been studied in a number of different ...
Joy Ross, Julia Riley, Joanne Droney
openaire +3 more sources