Results 91 to 100 of about 52,122 (312)
Фармация и фармакология (Пятигорск)Kappa opioid receptors play a pivotal role in regulating both physiological and cognitive processes. RU-1205, a benzimidazole derivative acting as a specific kappa opioid receptor agonist, has demonstrated the capacity to modulate neuronal activity ...
K. Yu. Kalitin +2 more
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PLoS ONE, 2014 BackgroundAn opioid peptide neuron/humoral feedback regulation might be involved in changes of intraocular pressure (IOP). The aims of this study are to investigate the effects of arcuate nucleus (ARC) and opioid peptides on intraocular pressure (IOP ...
Ji Jin, Guo-xu Xu, Zhi-lan Yuan
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, 2010 Amanzio and Benedetti (J Neurosci 1999; 19: 484-494) first addressed the conditions necessary for the activation of opioid and non-opioid placebo responses in human. Here, we investigated whether placebo analgesia is subdivided into opioid and non-opioid
Wang, JY, Guo, JY, Luo, F, Luo F
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Veterinary Record, EarlyView.Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö +3 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2016 Social play behavior is a highly rewarding, developmentally important form of social interaction in young mammals. However, its neurobiological underpinnings remain incompletely understood.
Antonia Manduca +9 more
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, 2015 Treatments for neuropathic pain are either not fully effective or have problematic side effects. Combinations of drugs are often used. Tapentadol is a newer molecule that produces analgesia in various pain models through two inhibitory mechanisms, namely
Gonçalves, L, Friend, LV, Dickenson, AH
core
Innovations in agonist maintenance treatment of opioid-dependent patients
, 2006 PURPOSE OF REVIEW: To provide an overview of published studies on agonist maintenance treatment options for opioid-dependent patients. RECENT FINDINGS: The recent publication of controlled trials confirms earlier clinical evidence of the efficacy of ...
Haasen, Christian, van den Brink, Wim
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Field immobilisation of adult Weddell seals using intramuscular butorphanol and midazolam
Veterinary Record, EarlyView.Abstract Background When working with free‐ranging phocid seals, methods of chemical immobilisation require ongoing refinement to reduce complications, particularly apnoea, during research procedures. Methods Adult Weddell seals (n = 20) at Cape Crozier, Antarctica, were chemically immobilised with intramuscular injection of butorphanol and midazolam ...
Rachel R. Holser +5 more
wiley +1 more source
Social trauma and the mu-opioid system in depression
, 2011 The overarching thesis under investigation is that the endogenous opioid system plays a key role in depression subsequent to traumatic childhood social experiences. This is suggested by the fact that animal work indicates that mu-opioids robustly mediate
Malcolm-Smith, Susan
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Journal of Forensic Sciences, EarlyView.Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou +4 more
wiley +1 more source