Results 101 to 110 of about 52,122 (312)

Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans

, 2007
The aim of this study was to investigate local opioid effects in the inflamed skin of healthy human volunteers. To induce inflammation, the circular tip of a 10-mm-diameter probe was heated to 48°C and applied for 120 seconds to a site on each forearm of
Hammond, G.R., Drummond, P.D., Robertson, L.   +2 more
core  

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Chronic Inflammatory Injury Results in Increased Coupling of Delta Opioid Receptors to Voltage-Gated Ca Channels

Molecular Pain, 2013
Background Opioid receptors regulate a diverse array of physiological functions. Mu opioid receptor agonists are well-known analgesics for treating acute pain.
Amynah Pradhan, Monique Smith, Brenna McGuire, Christopher Evans, Wendy Walwyn   +4 more
doaj   +1 more source

Effects of Loperamide on Mechanical Allodynia Induced by Herpes Simplex Virus Type-1 in Mice

Journal of Pharmacological Sciences, 2007
In the present study, we investigated whether the peripherally acting µ-opioid receptor agonist loperamide would inhibit allodynia in the non-inflamed dermatome of mice with herpetic pain.
Atsushi Sasaki, Yasutaka Nakashima, Ichiro Takasaki, Tsugunobu Andoh, Kimiyasu Shiraki, Yasushi Kuraishi   +5 more
doaj   +1 more source

Association of opioid agonist therapy with the initiation of antiretroviral therapy - a systematic review

, 2016
ObjectivesPeople who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART).
Ubuguyu, Omary Said, Jimba, Masamine, Sunguya, Bruno Fokas, Yasuoka, Junko, Mbwambo, Jessie Kazeni Kilonzo, Mlunde, Linda Beatrice   +5 more
core   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

Addiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock, Krista J. Siefried, Gill Bedi, Steven Albert, Richard O. Day, Nadine Ezard, Margaret Ross, Paul Liknaitzky, Jonathan Brett   +8 more
wiley   +1 more source

The effect of subcutaneous naloxone on experimentally induced pain

, 2008
The heat pain threshold was assessed in 32 healthy participants after a mild burn on the dorsal surface of each hand, after injection of an opioid antagonist (80 μg naloxone) or vehicle alone (0.2 mL saline) into the burnt skin of 1 hand, and after ...
Hammond, G.R., Drummond, P.D., Robertson, L.   +2 more
core  

Characteristics of admitted patients either receiving or not receiving opioid agonist therapy for opioid use disorder, 2014–17.

, 2019
Characteristics of admitted patients either receiving or not receiving opioid agonist therapy for opioid use disorder, 2014–17.
Justin C. Yang (6882941), Carol Brayne (17434), Andres Roman-Urrestarazu (5447288)   +2 more
core   +1 more source

Full agonist opioid prescribing by primary care clinicians after buprenorphine training

, 2020
Background: While primary care clinicians are being trained to use buprenorphine for the treatment of Opioid Use Disorder (OUD) in order to increase access to addiction treatment, it is not known what impact such training and subsequent experience ...
Jenkins, Paul, Anderson, James, Chung, Yelim K, Krupa, Nicole, Gadomski, Anne   +4 more
core   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark, Kevin M. Gray, Nathaniel L. Baker, Brian J. Sherman, Bryan Tolliver, Jessica Burt, Alonzo Steplight, Elizabeth Chapman, Amanda Wagner   +8 more
wiley   +1 more source