Results 131 to 140 of about 52,122 (312)
Beyond abstinence: Redefining success in cannabis use disorder treatment
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin +3 more
wiley +1 more source
We review clinical care issues that are related to illicit and therapeutic opioid use among pregnant women and women in the postpartum period and outline the major responsibilities of obstetrics providers who care for these patients during the antepartum,
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Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley +1 more source
Place of buprenorphine in the management of opioid dependence
Buprenorphine is a partial agonist at μ opioid receptors and has been used extensively in pain management. Its use in the management of opioid dependence has occurred in the last decade although its potential has been recognized from the late 1970s ...
Mattick, Richard P. +2 more
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OBJECTIVE: We aimed to quantify the effect of opioid agonist pharmacotherapy on pain management after cesarean delivery, compared with patients not on these medications.
Cobb, Johanna +6 more
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ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
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Opioid agonist treatment for pharmaceutical opioid dependent people (Protocol)
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of maintenance agonist pharmacotherapy treatments for the treatment of pharmaceutical opioid ...
Linda Gowing (20229114) +5 more
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Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors
1. In the present study, we examined the pharmacological activity of the putative kappa3-opioid receptor agonist naloxone benzoylhydrazone (NalBzoH) at recombinant human opioid receptors individually expressed in Chinese hamster ovary (CHO) cells and ...
ONALI, PIER LUIGI +5 more
core +1 more source
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy +19 more
wiley +1 more source

