Results 141 to 150 of about 52,122 (312)

Pharmacological enhancement of naltrexone treatment for opioid dependence: a review

Substance Abuse and Rehabilitation, 2011
Paolo Mannelli, Kathleen S Peindl, Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USAPurpose: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that ...
Peindl K, Mannelli P, Wu LT
doaj  

Activation of the Carotid Body by Kappa Opioid Receptors Mitigates Fentanyl-Induced Respiratory Depression

Function
Previous studies reported that opioids depress breathing by inhibiting respiratory neural networks in the brainstem. The effects of opioids on sensory inputs regulating breathing are less studied.
Ying-Jie Peng, Jayasri Nanduri, Ning Wang, Zheng Xie, Aaron P Fox, Nanduri R Prabhakar   +5 more
doaj   +1 more source

A case of fatal overdose following inpatient detoxification: The problematic role of rapid opioid agonist tapers for opioid use disorder

, 2017
BACKGROUND: Relapse to opioid use is common after rapid opioid withdrawal. As a result, short-term tapers of opioid agonist/partial agonist medications, such as methadone and buprenorphine/naloxone, are no longer recommended by recent clinical care ...
Jan Klimas, Wood, Evan, Derek C. Chang, Evan Wood, Chang, Derek, Fairbairn, Nadia, Nadia Fairbairn, Klimas, Jan   +7 more
core   +1 more source

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Prophylactic interventions to prevent rebound pain after peripheral nerve block in adults: a systematic review and network meta‐analysis of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction Rebound pain after peripheral nerve block is recognised increasingly as a postoperative complication that may diminish the benefits of regional anaesthesia. We undertook a systematic review and network meta‐analysis to evaluate pharmacological strategies for its prevention.
Narinder Pal Singh, Jeetinder Kaur Makkar, Chelsea Zhang, Anuradha Borle, Preet Mohinder Singh   +4 more
wiley   +1 more source

Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density

, 2004
The effects of kappa-opioid agonist treatment on kappa-opioid receptor density and on dynorphin A levels in the rat brain were studied. Rats were treated with the selective kappa-opioid agonist U-69593 or vehicle for 5 d.
ROMUALDI P., CANDELETTI, SANZIO, IZENWASSER S., DADDARIO C., DI BENEDETTO M., CANDELETTI S., ROMUALDI, PATRIZIA, D'ADDARIO, Claudio, DI BENEDETTO, MANUELA, Izenwasser, Sari   +9 more
core   +1 more source

Response to Crockford et al.: Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

Addiction, EarlyView.
Nathaniel Day, Shelly Vik, Robert Tanguay, Nickie Mathew, Anees Bahji   +4 more
wiley   +1 more source

Beyond the Epidural: Reframing Analgesia for the Modern Oesophagectomy

ANZ Journal of Surgery, EarlyView.
A novel analgesic framework for minimally invasive oesophagectomy to facilitate functional recovery.
William Thomas Birkett, Geraldine Ooi, Bethany White, Hamish Shilton, Liang Low, Paul Cashin, Walston Reginald Martis   +6 more
wiley   +1 more source

Regulation of dynorphin gene expression by kappa-opioid agonist treatment

, 2002
The effects of K-opioid agonist treatment on prodynorphin mRNA expression in the rat brain were studied. Rats were treated with the selective kappa-opioid agonist U-69593 or vehicle for 5 days and prodynorphin mRNA was measured on day 8 (3 days after the
IZENWASSER S., COLLINS S, ROMUALDI P, CANDELETTI S, D'ADDARIO, Claudio   +4 more
core  

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

Australian Veterinary Journal, EarlyView.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley   +1 more source