Results 241 to 250 of about 292,142 (337)

Comparative effectiveness of urine drug testing schedules alongside opioid agonist treatment: Emulation of a population-based target trial in British Columbia, Canada. [PDF]

Addiction
Kurz M, Guerra-Alejos BC, Min JE, Seaman SR, Piske M, Bach P, Bruneau J, Greenland S, Gustafson P, Kampman K, Karim ME, Korthuis PT, Platt RW, Siebert U, Socías ME, Wood E, Nosyk B.   +16 more
europepmc   +1 more source

Use of Semaglutide and Tirzepatide in Rheumatic and Musculoskeletal Diseases: Insights on Initiation Patterns and Weight Loss From the Rheumatology Informatics System for Effectiveness Registry

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) such as semaglutide (SEM) and tirzepatide (TZP) were initially approved for type 2 diabetes management but are increasingly used for weight loss. Limited data exist on real‐world use among patients with rheumatic and musculoskeletal diseases (RMDs).
Nicholas P. McCormick, Cristiano S. Moura, Jingyi Zhang, Emily E. Holladay, Fenglong Xie, Tapan Mehta, Joshua F. Baker, Jeffrey R. Curtis   +7 more
wiley   +1 more source

Correction: Psychiatrist-led hepatitis C (HCV) treatment at an opioid agonist treatment clinic in Stockholm- a model to enhance the HCV continuum of care. [PDF]

BMC Psychiatry
Klasa PE, Sandell M, Aleman S, Kåberg M.   +3 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Identifying opioid agonist treatment prescriber networks from health administrative data: A validation study. [PDF]

PLoS One
Kurz M, Tatangelo M, Morin KA, Zanette M, Krebs E, Marsh DC, Nosyk B.   +6 more
europepmc   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source

Challenges for the implementation of injectable opioid agonist treatment: a scoping review. [PDF]

Harm Reduct J
Schwarz T, Akartuna D, Busch M, Krausz RM, Uhl A.   +4 more
europepmc   +1 more source

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Many people use cannabis to self‐medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta‐9‐tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our previous research with the opioid morphine suggests persistent pain will increase the magnitude and duration of
Michael M. Morgan, Christa M. Hickey
wiley   +1 more source

Initiation of opioid agonist treatment following hospital-treated opioid toxicities and the risk of repeat events in Ontario, Canada: a cohort study using inverse probability of treatment weights. [PDF]

BMJ Public Health
Ledlie S, Tadrous M, Bayoumi AM, McCormack D, Kent JT, Besharah J, Munro C, Gomes T.   +7 more
europepmc   +1 more source

Behavioural Characterisation and Pharmacological Validation of an Incisional Wound‐Related Pain Model

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Wound‐related pain represents a significant unmet clinical need. To advance its understanding and treatment, there is a need for a validated preclinical model for the study of wound‐related pain in both sexes. Methods A 1.2 cm incision was created on the hairy skin of the dorsum of male and female Sprague–Dawley rats posterior to L4.
Catherine R. Healy, Maria C. Redmond, Mary Hopkins, Georgina Gethin, Abhay Pandit, David P. Finn   +5 more
wiley   +1 more source