Results 221 to 230 of about 7,007,196 (291)

Acute Pain During Intensive Care: Prevalence, Predisposing Factors and Pain Trajectories. A Prospective Multicenter Observational Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background A considerable proportion of patients in the intensive care unit (ICU) experience pain. The objective of this prospective observational cohort study was to investigate the prevalence of pain, factors associated with pain and pain trajectories in ICU patients.
Aleksandra E. Wlodarczyk‐Abou Elseoud   +7 more
wiley   +1 more source

Comparative effectiveness of missed dose protocols of opioid agonist treatment in British Columbia, Canada: protocol for a population-based target trial emulation. [PDF]

open access: yesBMJ Open
Mondol MH   +11 more
europepmc   +1 more source

The Use of Intravenous Clonidine in Postoperative Pain Management: A Scoping Review

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Clonidine, an alpha‐2 receptor agonist, has been explored as a potential analgesic in postoperative pain management, but its efficacy and safety profile remain unclear. The aim of this scoping review was to present the evidence on the use of intravenous clonidine in postoperative pain management.
Tórálvur Mohr   +4 more
wiley   +1 more source

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

open access: yesAddiction, Volume 121, Issue 10, Page 2607-2619, October 2026.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw   +5 more
wiley   +1 more source

Comparative effectiveness of take-home dosing schedules for opioid agonist treatment in British Columbia, Canada: a target trial emulation protocol using a population-based observational study. [PDF]

open access: yesBMJ Open
Kurz M   +18 more
europepmc   +1 more source

Factors associated with the percentage of individuals who initiate and discontinue naltrexone as a relapse prevention pharmacotherapy in opioid use disorder: A systematic review, meta‐analysis and meta‐regression

open access: yesAddiction, Volume 121, Issue 10, Page 2620-2632, October 2026.
Abstract Background and aims Naltrexone is a pharmacotherapeutic option for relapse prevention in opioid use disorder (OUD); however, studies highlight low rates of initiation and high rates of discontinuation as limiting its effectiveness. We aimed to (1) estimate the percentage of individuals with OUD who (having undergone withdrawal and wish to ...
Emmert Roberts   +5 more
wiley   +1 more source

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