Correction: Psychiatrist-led hepatitis C (HCV) treatment at an opioid agonist treatment clinic in Stockholm- a model to enhance the HCV continuum of care. [PDF]
Klasa PE +3 more
europepmc +1 more source
Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez +6 more
wiley +1 more source
Identifying opioid agonist treatment prescriber networks from health administrative data: A validation study. [PDF]
Kurz M +6 more
europepmc +1 more source
ABSTRACT Introduction The Syphilis Point of care Rapid testing and Immediate Treatment Evaluation (SPRITE) is a collaborative, community‐based initiative that strengthens syphilis prevention and control in Ontario, Canada through flexible outreach nursing and point‐of‐care testing (POCT) and immediate treatment.
Megan Ann Carter +13 more
wiley +1 more source
Cohort profile: the provincial opioid agonist treatment cohort in Ontario, Canada. [PDF]
Morin KA +3 more
europepmc +1 more source
ABSTRACT Background Preoperative anxiety is common in children and is associated with emergence delirium—a distressing postoperative complication characterized by agitation and disorientation. Midazolam has long been the drug of choice for preoperative anxiolysis.
Anne Louise de Barros Garioud +7 more
wiley +1 more source
Initiation of opioid agonist treatment following hospital-treated opioid toxicities and the risk of repeat events in Ontario, Canada: a cohort study using inverse probability of treatment weights. [PDF]
Ledlie S +7 more
europepmc +1 more source
Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley +1 more source
Exploring the early impacts of drug decriminalization on harm reduction and opioid agonist treatment service operations and delivery in British Columbia: insights from key informant interviews. [PDF]
Russell C +11 more
europepmc +1 more source
ABSTRACT Opioid receptor antagonists increase the plasma membrane density of μ‐opioid receptors (MOR) in vivo, thereby inducing “supersensitivity” to opioid agonists. This phenomenon increases the risk of overdose in patients that were being treated with naltrexone (Ntx), a popular MOR antagonist.
Stephen N. Grant +2 more
wiley +1 more source

