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Parenthood and opioid dependence [PDF]

open access: yesSubstance Abuse and Rehabilitation, 2015
Heljä Pihkala, Mikael Sandlund Institution of Clinical Sciences/Psychiatry, Umeå University, Umeå, Sweden Introduction: Many patients in maintenance treatment programs for opioid dependence are parents to underage children.
Pihkala H, Sandlund M
doaj   +2 more sources

Long-term agonist and antagonist therapy for adolescent opioid dependence: A description of two cases

open access: yesIndian Journal of Psychological Medicine, 2014
Adolescents constitute only a small percentage of treatment seekers in drug dependence treatment settings. Little research evidence is available for pharmacological treatment of adolescent opioid dependence and no prior case report is available from ...
Rajeev Ranjan   +2 more
doaj   +1 more source

Prevalence of Opioid Dependence and Opioid Agonist Treatment in the Berlin Custodial Setting: A Cross-Sectional Study

open access: yesFrontiers in Psychiatry, 2020
BackgroundAmong people living in detention, substance use is highly prevalent, including opioid dependence. Opioid agonist treatment (OAT) has been established as an evidence-based, first-line treatment for opioid dependence.
Kira von Bernuth   +6 more
doaj   +1 more source

Single high-dose buprenorphine for opioid craving during withdrawal

open access: yesTrials, 2018
Background Opioid use disorder is one of the most prevalent addiction problems worldwide. Buprenorphine is used as a medication to treat this disorder, but in countries where buprenorphine is unavailable in combination with naloxone, diversion can be a ...
Jamshid Ahmadi   +3 more
doaj   +1 more source

Spatial transcriptomics reveals distinct cell type dynamics following opioid dependence in female mice with the common human μ-opioid receptor variant Oprm1 A118G

open access: yesNature Communications
Opioid Use Disorder (OUD) is a complex neuropsychiatric condition shaped by multiple factors including genetics. The A118G single-nucleotide polymorphism (rs1799971) in the µ-opioid receptor gene (OPRM1) has been associated with heightened risk for ...
Yihan Xie   +9 more
doaj   +1 more source

Exploring genetic predictors of naltrexone treatment response in opioid use disorder

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019
Purpose: The present study was aimed to evaluate the effect of the opioid receptors genes and dopamine system genes polymorphisms on the treatment outcomes of opioid dependence with implantable and oral naltrexone in randomized double blinded double ...
Е. A. Blokhina .   +6 more
doaj   +1 more source

25 years of studies on the efficacy and safety of different formulations of naltrexone for the opioid use disorder treatment

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The article overviews the results of the studies of different formulations of opioid antagonist naltrexone (oral, injectable and implantable) for stabilization of remission and relapse prevention in patients with opioid dependence conducted by authors ...
E. M. Krupitsky   +3 more
doaj   +1 more source

Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls

open access: yesBMC Psychiatry, 2006
Background Individuals with opioid dependence have cognitive deficits during abuse period in attention, working memory, episodic memory, and executive function.
Kähkönen Seppo   +6 more
doaj   +1 more source

Why do we need to control alcohol use through legislative measures? A south east asia perspective?

open access: yesIndian Journal of Community Medicine, 2010
Background: Even though prevalence of alcohol use in the world is very high, it has not been brought under legal control in several countries, contrary to other controlled substances like opium, cocaine, cannabis, and so on.
Saddichha Sahoo   +2 more
doaj  

Common Mechanisms Underlying Opioid Tolerance and Dependence and Neuropathic Pain: Role of Metabotropic Glutamate Receptors

open access: yesPain Research and Management, 2000
It has been suggested that opioid tolerance and dependence share common mechanisms with neuropathic pain. This short review deals with the role of glutamate and glutamate receptors in opioid tolerance and dependence, and neuropathic pain.
Marian E Fundytus
doaj   +1 more source

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