Results 1 to 10 of about 1,303 (113)
Parenthood and opioid dependence
Heljä Pihkala, Mikael Sandlund Institution of Clinical Sciences/Psychiatry, Umeå University, Umeå, Sweden Introduction: Many patients in maintenance treatment programs for opioid dependence are parents to underage children.
Pihkala H, Sandlund M
doaj +6 more sources
This review will introduce the concept of toll-like receptor (TLR)–mediated glial activation as central to all of the following: neuropathic pain, compromised acute opioid analgesia, and unwanted opioid side effects (tolerance, dependence, and reward ...
Mark R. Hutchinson +5 more
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Buprenorphine for Opioid Dependence [PDF]
Buprenorphine is a partial mu agonist opioid that is FDA-approved to manage opioid addiction in settings outside of traditional methadone clinics. The clinical uses, pharmacokinetics, pharmacodynamics, toxicology, and management of overdoses of buprenorphine are reviewed.
Megan, Milne +2 more
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Relapse in opioid dependence: Role of psychosocial factors
Background: Although our understanding about neurobiology of opioid dependence and availability of pharmacological treatment has gone a long way in the last few decades, psychosocial interventions play a pivotal role in the prevention of relapse owing to
Kailash Sureshkumar +3 more
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Compulsivity in opioid dependence [PDF]
This study aimed to investigate the relationship between compulsivity versus impulsivity and structural MRI abnormalities in opioid dependence.We recruited 146 participants: i) patients with a history of opioid dependence due to chronic heroin use (n=24), ii) heroin users stabilised on methadone maintenance treatment (n=48), iii) abstinent participants
Tolomeo, Serenella +3 more
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Dopamine D1 receptor gene variation modulates opioid dependence risk by affecting transition to addiction. [PDF]
Dopamine D1 receptor (DRD1) modulates opioid reinforcement, reward, and opioid-induced neuroadaptation. We propose that DRD1 polymorphism affects susceptibility to opioid dependence (OD), the efficiency of transition to OD, and opioid-induced pleasure ...
Feng Zhu +9 more
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Background: The relationship between the level of motivation and personality disorder (PD) in patients with opioid dependence syndrome is understudied.
Manu Sharma +3 more
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Background As dispensings for benzodiazepines and gabapentinoids have increased in recent years, risk of increased mortality has been identified, particularly when used with opioids. There is limited research examining use of these medicines among people
Chrianna Bharat +6 more
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Category: Other Introduction/Purpose: Surgeon prescription of narcotic medications has been identified as a contributor to the nation’s devastating opioid epidemic. The purpose of this study is to identify risk factors for postoperative opioid dependence
Daniel D. Bohl MD, MPH +6 more
doaj +1 more source
Genetics of Opioid Dependence: A Review of the Genetic Contribution to Opioid Dependence [PDF]
This narrative review aims to provide an overview of the impact of opioid dependence and the contribution of genetics to opioid dependence. Epidemiological data demonstrate that opioid dependence is a global trend with far-reaching effects on the social, economic, and health care systems.
Mistry, Chetna J +4 more
openaire +2 more sources

