Results 31 to 40 of about 1,267,582 (207)

Determining the impact of opioid substitution therapy upon mortality and recidivism among prisoners: a 22 year data linkage study [PDF]

, 2014
Foreword: Prisoners experience high rates of drug dependence, health problems and premature mortality. Without intervention, they often come into further contact with the criminal justice system, creating further health risk.
Natasa Gisev, Weatherburn, Don J., Burns, L., Lucy Burns, Louisa Degenhardt, Degenhardt, L., Gisev, Natasha, Mattick, R., Tony Butler, Weatherburn, Don, Kimber, J., Don Weatherburn, Kimber, Jo, Degenhardt, Louisa, Amy Gibson, Gisev, N., Larney, S ; https://orcid.org/, Gibson, Amy (R17420), Burns, Lucy, Larney, Sarah, Richard Mattick, Butler, Tony, Weatherburn, D., Dobbins, Tim, Gisev, N ; https://orcid.org/, Degenhardt, L ; https://orcid.org/, Tim Dobbins, Gibson, Amy, Weatherburn, D, Gibson, A., Mattick, RP, Larney, S., Gisev, Natasa, Jo Kimber, Dobbins, T ; https://orcid.org/, Mattick, Richard P., Dobbins, T., Sarah Larney, Kimber, J, Burns, L ; https://orcid.org/, Gibson, A ; https://orcid.org/, Butler, T ; https://orcid.org/, Dobbins, Timothy A., Mattick, Richard   +43 more
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Model performance metrics for opioid abuse/dependence/overdose prediction.

, 2023
Model performance metrics for opioid abuse/dependence/overdose prediction.
Ran S. Sun (16828148), Oualid El Hajouji (14223188), Catherine M. Curtin (9174708), Keith Humphreys (28187), Steven M. Asch (6307901), Alban Zammit (14223185), Ian Carroll (415150), Tina Hernandez-Boussard (4013)   +7 more
core   +1 more source

An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray

The Scientific World Journal, 2012
The chronic use of opiates (i.e., narcotics such as the natural derivatives of opium including morphine or codeine) or opioids (i.e., semisynthetic derivatives of opium and other molecules that activate opioid receptors) induces dependence, which is ...
Handong Ouyang, Shue Liu, Weian Zeng, Roy C. Levitt, Keith A. Candiotti, Shuanglin Hao   +5 more
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Predicting opioid dependence from electronic health records with machine learning

BioData Mining, 2019
Background The opioid epidemic in the United States is averaging over 100 deaths per day due to overdose. The effectiveness of opioids as pain treatments, and the drug-seeking behavior of opioid addicts, leads physicians in the United States to issue ...
Randall J. Ellis, Zichen Wang, Nicholas Genes, Avi Ma’ayan   +3 more
doaj   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

National opioid pharmacotherapy statistics 2014 [PDF]

, 2015
Summary Dependence on opioid drugs is associated with a range of health and social problems that affect individual drug users, their family and friends, and the wider public.
Australian Institute of Health and Welfare
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Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir, Jing Song, Lutfiyya N. Muhammad, Wendy Marder, Kevin Deane, Clifton Bingham, Lisa A. Mandl, Robert Edwards, Judith T. Moskowitz, Yvonne C. Lee   +9 more
wiley   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

National opioid pharmacotherapy statistics annual data collection 2012 [PDF]

, 2013
On a snapshot day in 2012, almost 47,000 clients received pharmacotherapy treatment for their opioid dependence at 2,226 dosing points around Australia, this report finds.SummaryAlmost 47,000 Australians received pharmacotherapy treatment for their ...

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