Mechanism of opioid addiction and its intervention therapy: Focusing on the reward circuitry and mu‐opioid receptor [PDF]
MedComm, 2022 Opioid abuse and addiction have become a global pandemic, posing tremendous health and social burdens. The rewarding effects and the occurrence of withdrawal symptoms are the two mainstays of opioid addiction.
Jia‐Jia Zhang +5 more
doaj +3 more sources
Restoring the neuroprotective capacity of glial cells under opioid addiction
Addiction Neuroscience, 2022 Opioid addiction is a worldwide public health crisis stemming from the well-intentioned efforts of physicians to improve pain management in the 1990’s.
Alexis C. Spencer +4 more
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Predisposing, enabling and reinforcing factors associated with opioid addiction helping behaviour in tri-state Appalachian counties: application of the PRECEDE–PROCEED model–cross-sectional analysis [PDF]
BMJ Open, 2023 Objectives The overdose epidemic was designated a ‘Public Health Emergency’ in the USA on 26 October 2017, bringing attention to the severity of this public health problem.
Richard W Kim +6 more
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An emerging multi-omic understanding of the genetics of opioid addiction [PDF]
The Journal of Clinical InvestigationOpioid misuse, addiction, and associated overdose deaths remain global public health crises. Despite the tremendous need for pharmacological treatments, current options are limited in number, use, and effectiveness.
Eric O. Johnson +16 more
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Frequency and Predictors of Opioid Use in Rheumatoid Arthritis and Seronegative Spondyloarthropathy Patients [PDF]
Addiction and Health, 2023 Background: Pain is one of the most challenging symptoms in patients with rheumatoid arthritis (RA) and spondyloarthropathies (SpAs), and pain relief is one of the top priorities for improving health-related quality of life.
Maryam Sahebari +4 more
doaj +1 more source
Post-Traumatic Risk Factors in Heroin Addiction Patients Undergoing Substitution Treatment
المجلة الدولية للعلوم الإنسانية والاجتماعية, 2021 Opioid addiction is a real public health problem and studies on its risk factors are needed. Scientific work addressing the links between heroin addiction from the angle of the impact of traumatic events and post-traumatic consequences, risk factors ...
Firas Abbas Fadhil
doaj +1 more source
Editorial: Optimizing opioid prescriptions in the emergency department
BMC Emergency Medicine, 2023 Optimizing opioid prescriptions in the emergency department is essential to address the opioid pandemic while ensuring patient wellbeing. This requires a comprehensive approach that includes exploring alternatives to opioids for pain management ...
Ashraf A. Dahaba, Rishi S. Nannan Panday
doaj +1 more source
Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism
Brain Sciences, 2023 Drug addiction is one of the major worldwide health problems, which will have serious adverse consequences on human health and significantly burden the social economy and public health.
Liyun Deng +5 more
doaj +1 more source
PLoS ONE, 2013 It is becoming increasingly evident that genetic variants contribute to the development of opioid addiction. An elucidation of these genetic factors is crucial for a better understanding of this chronic disease and may help to develop novel therapeutic ...
Beate Beer +6 more
doaj +1 more source
Psychiatry and Clinical Psychopharmacology, 2019 OBJECTIVE: Opioid addiction is a disease that is increasing in our country, Turkey, and around the world, which it is difficult to treat in medical, social, and economic terms.
Özlem Çıtak Ekici +5 more
doaj +1 more source