Results 11 to 20 of about 369,622 (191)
Management of opioid addiction with buprenorphine: French history and current management
International Journal of General Medicine, 2014 Pierre Poloméni,1 Raymund Schwan2,3 1Department of Addictology, Paris Seine Saint Denis University Hospital, AP-HP, Site René Muret Sevran, France; 2Care Center for the Treatment and Prevention of Addictions (CSAPA), Nancy University ...
Poloméni P, Schwan R
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, 2018 An epidemic is a feeling set within time as much as it is a matter of statistics and epidemiology: it is the feeling of many of us in the same desperate place at the same desperate time. Opioid epidemic thus names a present moment — at once historic and historical — centered on the substance of opioids as much as it names the urgency of all of us who ...
Dolphin-Krute, Maia
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Glutamatergic Systems and Memory Mechanisms Underlying Opioid Addiction. [PDF]
Cold Spring Harb Perspect Med, 2021 Glutamate is the main excitatory neurotransmitter in the brain and is of critical importance for the synaptic and circuit mechanisms that underlie opioid addiction.
Heinsbroek JA, De Vries TJ, Peters J.
europepmc +2 more sources
Treating opioid addiction [PDF]
Canadian Medical Association Journal, 2012 Nosyk and colleagues[1][1] have analyzed data from the North American Opiate Medication Initiative (NAOMI)[2][2] in an attempt to ascertain cost-effectiveness of diacetylmorphine versus methadone among those “refractory to treatment” (people in whom “standard” methadone maintenance ...
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A Theory of Natural Addiction [PDF]
, 2007 Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Tasnádi, Attila +3 more
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Genetic Vulnerability to Opioid Addiction. [PDF]
Cold Spring Harb Perspect Med, 2021 Opioid addiction, also referred to as opioid use disorder, continues to be a devastating problem throughout the world. Familial relation and twin studies have revealed opioid addiction, like other addictive diseases, to be profoundly influenced by genetics.
Reed B, Kreek MJ.
europepmc +3 more sources
Epigenetic Mechanisms of Opioid Addiction [PDF]
Biological Psychiatry, 2020 Opioid use kills tens of thousands of Americans each year, devastates families and entire communities, and cripples the health care system. Exposure to opioids causes long-term changes to brain regions involved in reward processing and motivation, leading vulnerable individuals to engage in pathological drug seeking and drug taking that can remain a ...
Caleb J. Browne +3 more
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Medication-assisted therapy for opioid addiction [PDF]
, 2013 The “Medication-Assisted Therapy for Opioid Addiction” session was chaired by Dr Betty Tai and had three presenters. The presenters (and their topics) were: Dr Andrew J.
Saxon, Andrew J +5 more
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Opioid Pharmacogenetics of Alcohol Addiction [PDF]
Cold Spring Harbor Perspectives in Medicine, 2013 Alcohol addiction is one of the most common and devastating diseases in the world. Given the tremendous heterogeneity of alcohol-addicted individuals, it is unlikely that one medication will help nearly all patients. Thus, there is a clear need to develop predictors of response to existing medications.
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The Opioid-Addicted Tetrapartite Synapse [PDF]
Biological Psychiatry, 2020 Opioid administration in preclinical models induces long-lasting adaptations in reward and habit circuitry. The latest research demonstrates that in the nucleus accumbens, opioid-induced excitatory synaptic plasticity involves presynaptic and postsynaptic elements as well as adjacent astroglial processes and the perisynaptic extracellular matrix.
Anna Kruyer +2 more
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