Is the promise of methadone Kenya's solution to managing HIV and addiction? A mixed-method mathematical modelling and qualitative study. [PDF]
BACKGROUND AND OBJECTIVES: Promoted globally as an evidence-based intervention in the prevention of HIV and treatment of heroin addiction among people who inject drugs (PWID), opioid substitution treatment (OST) can help control emerging HIV epidemics ...
Guise, Andy +9 more
core +1 more source
Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?. [PDF]
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core +6 more sources
Predictors of relapse in patients with opioid addiction during buprenorphine-naloxone maintenance treatment [PDF]
Background: Opioid abuse is an important public health issue. Buprenorphine-Naloxone Combination (BNC) is one of the most efficacious approaches for opioid withdrawal.
Yalınçetin, Nilüfer +6 more
core +1 more source
Providers’ Perceptions of Chiropractic Care in Treatment of Opioid Addiction [PDF]
Fifteen hundred people in the United States die each week from opioid-related overdoses. In addition, the U.S. court system has been inundated with individuals facing legal proceedings, with opioid addiction, impacted competency, and recidivism.
Khan, Rebekah Jan
core +1 more source
Developing a comprehensive inventory to define harm reduction housing
Background The City of Boston has faced unprecedented challenges with substance use amidst changes to the illicit drug supply and increased visibility of homelessness.
Sofia Zaragoza +9 more
doaj +1 more source
Co-morbid pain and opioid addiction: long term effect of opioid maintenance on acute pain
INTRODUCTION: Medication assisted treatment for opioid dependence alters the pain experience. This study will evaluate changes pain sensitivity and tolerance with opioid treatments; and duration of this effect after treatment cessation.
Gonzalez, Gerardo, Wachholtz, Amy B.
core +1 more source
Real time, on-site drug checking in low-threshold housing communities
Background In recent years, Boston has attempted to increase housing options and reduce overdose risk through the implementation of harm reduction housing (HRH) sites.
Charlie Summers +6 more
doaj +1 more source
The global opioid crisis necessitates innovative non-pharmacological interventions for pain management and addiction recovery. This comprehensive narrative review synthesizes evidence from approximately 75 studies supporting manual therapy’s modulation ...
Hyunjoong Kim
doaj +1 more source
Mechanisms of opioids and evaluation on existing therapies for addiction [PDF]
This research explores the intricate mechanisms of opioid action and evaluates a diverse of different therapeutic approaches for in the treatment of the opioid addiction.
Kong Yitian
doaj +1 more source
The Anesthetic Implications of Opioid Addiction
With the increasing availability of highly addictive, relatively cheap opioids in tablet form, the classic picture of the patient-addict has changed. Opioid-addicted patients often present for surgery and require anesthesia services.
Michael Lewis +3 more
core +1 more source

